The Endocannabinoid Anandamide Modulates Adhesion, Proliferation and The Production Of Inflammatory Mediators In Rheumatoid Arthritis Synovial Fibroblasts By Activating CB1, TRPV1, TRPA1 and Non-Cannabinoid Receptor Targets

被引：0
|
作者：
Lowin, Torsten [1 ]
Graeber, Angelika [1 ]
Straub, Rainer H. [1 ]
机构：
[1] Univ Hosp Regensburg, Lab Exp Rheumatol & Neuroendocrinoimmunol, Regensburg, Germany
来源：
ARTHRITIS AND RHEUMATISM | 2013年 / 65卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
930
引用
收藏
页码：S398 / S399
页数：2
相关论文
共 15 条
  • [1] The endocannabinoid anandamide modulates adhesion, proliferation and the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating CB1, TRPV1 and non-cannabinoid receptor targets
    Lowin, T.
    Graeber, A.
    Straub, R.
    ZEITSCHRIFT FUR RHEUMATOLOGIE, 2013, 72 : 106 - 106
  • [2] The synthetic cannabinoid and CB1/CB2 agonist WIN55212,2 decreases the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating TRPV1 and non-cannabinoid receptor targets
    Lowin, Torsten
    Graeber, Angelika
    Straub, Rainer H.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2013, 31 (05) : 833 - 833
  • [3] The synthetic cannabinoid WIN55,212-2 mesylate decreases the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating CB2, TRPV1, TRPA1 and yet unidentified receptor targets
    Lowin, Torsten
    Pongratz, Georg
    Straub, Rainer H.
    JOURNAL OF INFLAMMATION-LONDON, 2016, 13
  • [4] The synthetic cannabinoid WIN55,212-2 mesylate decreases the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating CB2, TRPV1, TRPA1 and yet unidentified receptor targets
    Torsten Lowin
    Georg Pongratz
    Rainer H. Straub
    Journal of Inflammation, 13
  • [5] The cannabinoid CB1 receptor and the endocannabinoid anandamide: possible antidepressant targets
    Bambico, Francis Rodriguez
    Gobbi, Gabriella
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2008, 12 (11) : 1347 - 1366
  • [6] The endocannabinoid/endovanilloid anandamide regulates proliferation and apoptosis of human keratinocytes via novel signaling interactions between vanilloid receptor-1 (TRPV1) and cannabinoid receptor-1 (CB1)
    Biro, T.
    Dajnoki, A.
    Telek, A.
    Bodo, E.
    Dobrosi, N.
    Toth, B. I.
    Paus, R.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2006, 126 : 95 - 95
  • [7] Affinin, Isolated from Heliopsis longipes, Induces an Antihypertensive Effect That Involves CB1 Cannabinoid Receptors and TRPA1 and TRPV1 Channel Activation
    Luz-Martinez, Beatriz A.
    Marrero-Morfa, Dailenys
    Luna-Vazquez, Francisco J.
    Rojas-Molina, Alejandra
    Ibarra-Alvarado, Cesar
    PLANTA MEDICA, 2024, 90 (05) : 380 - 387
  • [8] Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner
    Torsten Lowin
    Martin Apitz
    Sven Anders
    Rainer H. Straub
    Arthritis Research & Therapy, 17
  • [9] Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with osteoarthritis and rheumatoid arthritis
    Engler, Andrea
    Aeschlimann, Andre
    Simmen, Beat R.
    Michel, Beat A.
    Gay, Renate E.
    Gay, Steffen
    Sprott, Haiko
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 359 (04) : 884 - 888
  • [10] Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner
    Lowin, Torsten
    Apitz, Martin
    Anders, Sven
    Straub, Rainer H.
    ARTHRITIS RESEARCH & THERAPY, 2015, 17
12