Vitamin D Deficiency Is Common Among HIV-Infected Breastfeeding Mothers in Pune, India, but Is Not Associated With Mother-to-Child HIV Transmission

被引：7

作者：

Mave, Vidya ^{[1
,2
]}

Shere, Dhananjay ^{[1
]}

Gupte, Nikhil ^{[1
,2
]}

Suryavanshi, Nishi ^{[1
]}

Kulkarni, Vandana ^{[1
]}

Patil, Sandesh ^{[1
]}

Khandekar, Medha

Kinikar, Aarti

Bharadwaj, Renu

Bhosale, Ramesh

Sambarey, Pradeep

Chandanwale, Ajay

Bollinger, Robert ^{[2
,3
]}

Gupta, Amita ^{[2
,3
]}

机构：

[1] Byramjee Jeejeebhoy Med Coll, Clin Trials Unit, Pune, Maharashtra, India

[2] Johns Hopkins Sch Med, Baltimore, MD USA

[3] Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA

来源：

HIV CLINICAL TRIALS | 2012年 / 13卷 / 05期

关键词：

Vitamin D deficiency; HIV/AIDS; India; infant mortality; insufficiency; perinatal infection; pregnancy; maternal-child health; transmission; HYPOVITAMINOSIS-D; BONE METABOLISM; PREVALENCE; MORTALITY; PREGNANCY; IMMUNITY; INFANTS; SERUM;

D O I：

10.1310/hct1305-278

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A recent report from Tanzania demonstrated an increased risk of being HIV infected or of dying at birth among children born to breastfeeding mothers with low baseline vitamin D levels. We conducted a nested case-control study among HIV-infected pregnant women in western India to confirm the association between maternal vitamin D levels and mother-to-child transmission (MTCT) of HIV. Vitamin D insufficiency and deficiency were common among HIV-infected pregnant women, but were not associated with mother to child HIV transmission at 1 year postpartum (adjusted odds ratio [AOR] 0.66; 95% CI, 0.30-1.45; P=.30).

引用

页码：278 / 283

页数：6

共 28 条

[1] 1,25-DIHYDROXYVITAMIN-D3 AND THE REGULATION OF MACROPHAGE FUNCTION
BARSHAVIT, Z
NOFF, D
EDELSTEIN, S
MEYER, M
SHIBOLET, S
GOLDMAN, R
[J]. CALCIFIED TISSUE INTERNATIONAL, 1981, 33 (06) : 673 - 676
[2] Bedri A, 2008, LANCET, V372, P300, DOI 10.1016/S0140-6736(08)61114-9
[3] Bhalala U, 2007, INDIAN PEDIATR, V44, P897
[4] FREE 1,25-DIHYDROXYVITAMIN-D LEVELS IN SERUM FROM NORMAL SUBJECTS, PREGNANT SUBJECTS, AND SUBJECTS WITH LIVER-DISEASE
BIKLE, DD
GEE, E
HALLORAN, B
HADDAD, JG
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1984, 74 (06) : 1966 - 1971
[5] Assay variation confounds the diagnosis of hypovitaminosis D: A call for standardization
Binkley, N
Krueger, D
Cowgill, CS
Plum, L
Lake, E
Hansen, KE
DeLuca, HF
Drezner, MK
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2004, 89 (07) : 3152 - 3157
[6] CALCIUM HOMEOSTASIS AND BONE METABOLISM DURING PREGNANCY, LACTATION, AND POSTWEANING - A LONGITUDINAL-STUDY
CROSS, NA
HILLMAN, LS
ALLEN, SH
KRAUSE, GF
VIEIRA, NE
[J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1995, 61 (03) : 514 - 523
[7] Vitamin D and placental-decidual function
Evans, KN
Bulmer, JN
Kilby, MD
Hewison, M
[J]. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, 2004, 11 (05) : 263 - 271
[8] Food and Nutrition Board, 2010, DIET REF INT VIT D C
[9] The epidemiology of vitamin D and cancer incidence and mortality: A review (United States)
Giovannucci, E
[J]. CANCER CAUSES & CONTROL, 2005, 16 (02) : 83 - 95
[10] Goswami R, 2000, AM J CLIN NUTR, V72, P472

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