LongevityMap: a database of human genetic variants associated with longevity

被引：64

作者：

Budovsky, Arie ^{[1
,2
]}

Craig, Thomas ^{[3
]}

Wang, Jingwei ^{[3
]}

Tacutu, Robi ^{[3
]}

Csordas, Attila ^{[4
]}

Lourenco, Joana ^{[3
]}

Fraifeld, Vadim E. ^{[1
]}

de Magalhaes, Joao Pedro ^{[3
]}

机构：

[1] Ben Gurion Univ Negev, Ctr Multidisciplinary Res Aging, Shraga Segal Dept Microbiol Immunol & Genet, IL-84105 Beer Sheva, Israel

[2] Judea Reg Res & Dev Ctr, IL-90404 Carmel, Israel

[3] Univ Liverpool, Inst Integrat Biol, Integrat Genom Ageing Grp, Liverpool L69 7ZB, Merseyside, England

[4] European Mol Biol Lab, European Bioinformat Inst EMBL EBI, Cambridge CB10 1SD, England

来源：

TRENDS IN GENETICS | 2013年 / 29卷 / 10期

基金：

英国惠康基金;

关键词：

GWAS; humans; lifespan; polymorphisms;

D O I：

10.1016/j.tig.2013.08.003

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Understanding the genetic basis of human longevity remains a challenge but could lead to life-extending interventions and better treatments for age-related diseases. Toward this end we developed the LongevityMap (http://genomics.senescence.info/longevity/), the first database of genes, loci, and variants studied in the context of human longevity and healthy ageing. We describe here its content and interface, and discuss how it can help to unravel the genetics of human longevity.

引用

页码：559 / 560

页数：2

共 7 条

[1]

[Anonymous], 2013, DAT RES NAT CTR BIOT, DOI DOI 10.1093/NAR/GKS1189

[2] Biological evidence for inheritance of exceptional longevity [J].