Effect of Placenta Secretory Products on Migration Activity of Endothelial EA.Hy926 Cells

被引:0
|
作者
Stepanova, O. I. [1 ]
L'vova, T. Yu. [1 ]
Furaeva, K. N. [1 ]
Sokolov, D. I. [1 ]
Sel'kov, S. A. [1 ]
机构
[1] Russian Acad Med Sci, North Western Div, DO Ott Res Inst Obstet & Gynecol, St Petersburg, Russia
关键词
endothelial cells; migration; placenta; preeclampsia; ANGIOGENESIS; EXPRESSION; VEGF; ANGIOPOIETIN-1;
D O I
10.1007/s10517-013-2300-4
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
We studied the influence of factors secreted by the placenta in physiological and preeclampsia-complicated pregnancy on migration activity of endothelial EA.Hy926 cells. It was found that migration of endothelial cells was more intensive in the presence of secretory factors from trimester I placentas in comparison with trimester III placentas and was lower in the presence of placental factors in preeclampsia in comparison with physiological pregnancy.
引用
收藏
页码:156 / 160
页数:5
相关论文
共 50 条
  • [41] Differences between common endothelial cell models (primary human aortic endothelial cells and EA.hy926 cells) revealed through transcriptomics, bioinformatics, and functional analysis
    Wang, Dongdong
    Chen, Zhu
    Yeung, Andy Wai Kan
    Atanasov, Atanas G.
    CURRENT RESEARCH IN BIOTECHNOLOGY, 2021, 3 : 135 - 145
  • [42] A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA.hy926 endothelial cell line
    Aranda, Evelyn
    Owen, Gareth I.
    BIOLOGICAL RESEARCH, 2009, 42 (03) : 377 - 389
  • [43] Downregulation and inhibition of TRPM2 calcium channel prevent oxidative stress-induced endothelial dysfunction in the EA.hy926 endothelial cells model- Preliminary studies
    Arendt, Wioletta
    Piekarska, Klaudia
    Halas-Wisniewska, Marta
    Izdebska, Magdalena
    Grzanka, Alina
    Gagat, Maciej
    ADVANCES IN MEDICAL SCIENCES, 2025, 70 (01): : 62 - 78
  • [44] Synthesis and Use of pHEMA Microbeads With Human EA.hy 926 Endothelial Cells
    Nyangoga, Herve
    Zecheru, Teodora
    Filmon, Robert
    Basle, Michel-Felix
    Cincu, Corneliu
    Chappard, Daniel
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2009, 89B (02) : 501 - 507
  • [45] Effect of Monocyte-Like THP-1 Cells on the Formation of Vascular Tubes by EA.Hy926s Endothelial Cells in the Presence of Cytokines
    L'vova, T. Yu.
    Stepanova, O. I.
    Okorokova, L. S.
    Semenov, V. A.
    Rebezova, E. A.
    Sel'kov, S. A.
    Sokolov, D. I.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2015, 159 (01) : 146 - 151
  • [46] Sesamin Attenuates VEGFA-Induced Angiogenesis via Inhibition of Src and FAK Signaling in Chick Chorioallantoic Membrane Model and Human Endothelial EA.hy926 Cells
    Keratibumrungpong, Tanyaporn
    Srisuthtayanont, Warunee
    Wanachewin, Orawan
    Klangjorhor, Jeerawan
    Phitak, Thanyaluck
    Pothacharoen, Peraphan
    Shwe, Thuzar Hla
    Kongtawelert, Prachya
    BIOMEDICINES, 2023, 11 (01)
  • [47] Extracellular vesicles of U937 macrophage cell line infected with DENV-2 induce activation in endothelial cells EA.hy926
    Lucia Velandia-Romero, Myriam
    Angelica Calderon-Pelaez, Maria
    Balbas-Tepedino, Arturo
    Alejandro Marquez-Ortiz, Ricaurte
    Johana Madronero, L.
    Barreto Prieto, Alfonso
    Castellanos, Jaime E.
    PLOS ONE, 2020, 15 (01):
  • [48] MARCKS is involved in methylmercury-induced decrease in cell viability and nitric oxide production in EA.hy926 cells
    Cuong Van Dao
    Islam, Md. Zahorul
    Sudo, Kasumi
    Shiraishi, Mitsuya
    Miyamoto, Atsushi
    JOURNAL OF VETERINARY MEDICAL SCIENCE, 2016, 78 (10) : 1569 - 1576
  • [49] ELABELA improves endothelial cell functionviathe ELA-APJ axis by activating the PI3K/Akt signalling pathway in HUVECs and EA.hy926 cells
    Wang, Xiujuan
    Liang, Guoqing
    Guo, Qing
    Cai, Wei
    Zhang, Xin
    Ni, Jianmei
    Tao, Yanyan
    Niu, Xiulong
    Chen, Shaobo
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2020, 47 (12) : 1953 - 1964
  • [50] Angiogenesis related gene expression profiles of EA.hy926 cells induced by irbesartan: a possible novel therapeutic approach
    Ma Cong
    Lu Xue-chun
    Luo Yun
    Cao Jian
    Yang Bo
    Gao Yan
    Liu Xian-feng
    Fan Li
    CHINESE MEDICAL JOURNAL, 2012, 125 (08) : 1369 - 1375