Effect of Placenta Secretory Products on Migration Activity of Endothelial EA.Hy926 Cells

被引:0
|
作者
Stepanova, O. I. [1 ]
L'vova, T. Yu. [1 ]
Furaeva, K. N. [1 ]
Sokolov, D. I. [1 ]
Sel'kov, S. A. [1 ]
机构
[1] Russian Acad Med Sci, North Western Div, DO Ott Res Inst Obstet & Gynecol, St Petersburg, Russia
关键词
endothelial cells; migration; placenta; preeclampsia; ANGIOGENESIS; EXPRESSION; VEGF; ANGIOPOIETIN-1;
D O I
10.1007/s10517-013-2300-4
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
We studied the influence of factors secreted by the placenta in physiological and preeclampsia-complicated pregnancy on migration activity of endothelial EA.Hy926 cells. It was found that migration of endothelial cells was more intensive in the presence of secretory factors from trimester I placentas in comparison with trimester III placentas and was lower in the presence of placental factors in preeclampsia in comparison with physiological pregnancy.
引用
收藏
页码:156 / 160
页数:5
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