共 22 条
Lone atrial fibrillation as a positive predictor of left atrial volume reduction following ablation of atrial fibrillation
被引:13
作者:

Fredersdorf, Sabine
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机构:
Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany

Uecer, Ekrem
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Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany

Jungbauer, Carsten
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机构:
Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany

Dornia, Christian
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机构:
Univ Med Ctr Regensburg, Inst Rontgendiagnost, D-93053 Regensburg, Germany Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany

Eglmeier, Julia
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Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany

Eissnert, Christoph
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Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany

Hamer, Okka W.
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Univ Med Ctr Regensburg, Inst Rontgendiagnost, D-93053 Regensburg, Germany Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany

Weber, Stefan
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Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany

Arzt, Michael
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Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany

von Bary, Christian
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h-index: 0
机构:
Tech Univ Munich, Lehrkrankenhaus, Rotkreuzklinikum Munchen, D-80634 Munich, Germany Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany
机构:
[1] Univ Med Ctr Regensburg, Klin & Poliklin Innere Med 2, D-93053 Regensburg, Germany
[2] Univ Med Ctr Regensburg, Inst Rontgendiagnost, D-93053 Regensburg, Germany
[3] Tech Univ Munich, Lehrkrankenhaus, Rotkreuzklinikum Munchen, D-80634 Munich, Germany
来源:
EUROPACE
|
2014年
/
16卷
/
01期
关键词:
Arterial hypertension;
Lone atrial fibrillation;
Clinical predictor;
Left atrial volume reduction;
Ablation for atrial fibrillation;
PULMONARY VEIN ISOLATION;
MAGNETIC-RESONANCE ANGIOGRAPHY;
CATHETER ABLATION;
COMPUTED-TOMOGRAPHY;
ECHOCARDIOGRAPHY;
INJURY;
PVAC;
MRI;
D O I:
10.1093/europace/eut152
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Aims We investigated predictors of left atrial volume reduction (LAVR) in patients with atrial fibrillation (AF) undergoing AF ablation. Methods and results Sixty patients with AF underwent pulmonary vein isolation (PVI) using a pulmonary vein ablation catheter (PVAC). All patients underwent cardiac imaging by computed tomography or magnetic resonance imaging to determine LAV 1 day before and 140 +/- 9.5 days after PVI. Clinical follow-up and 72 h electrocardiogram Holter monitoring were performed 1, 3, and 6 months after ablation, and every 6 months thereafter. Significant LAVR (n = 60, 89.3 +/- 3.9 vs. 79.5 +/- 3.6 mL, P < 0.0001) was shown for the study group as a whole, caused particularly by the subgroup of patients with ablation success (n = 45, 85.2 +/- 4.6 vs. 72.5 +/- 3.7 mL, P < 0.0001). In addition, significant LAVR was shown for patients with lone AF (n = 25, 88.8 +/- 6.8 vs. 72.7 +/- 5.3 mL, P < 0.0001), but not for patients with AF and concomitant arterial hypertension (n = 32, 89 +/- 4.8 vs. 86.7 +/- 5 mL, P = 0.3), coronary artery disease (n = 12, 91.6 +/- 7.8 vs. 89.1 +/- 7.8 mL, P = 0.26), or left ventricular hypertrophy (n = 10, 86.3 +/- 5.5 vs. 83.1 +/- 5.3 mL, P = 0.27). Multivariate analysis revealed absence of arterial hypertension, lone AF, ablation success, and initial LA enlargement as independent predictors for significant LAVR following ablation (each P < 0.05). Conclusion Based on the subgroup of patients with lone AF, PVI leads to a significant LAVR 4 months after the procedure, especially in patients with clinical success in terms of AF freedom. Comorbidities such as arterial hypertension may prevent this reverse atrial remodelling, despite AF freedom. Clinical implications need to be further elucidated.
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页码:26 / 32
页数:7
相关论文
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McGann, Christopher J.
;
Kholmovski, Eugene G.
;
Oakes, Robert S.
;
Blauer, Joshua J. E.
;
Daccarett, Marcos
;
Segerson, Nathan
;
Airey, Kelly J.
;
Akoum, Nazem
;
Fish, Eric
;
Badger, Troy J.
;
DiBella, Edward V. R.
;
Parker, Dennis
;
MacLeod, Rob S.
;
Marrouche, Nassir F.
.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,
2008, 52 (15)
:1263-1271

McGann, Christopher J.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Utah, Sch Med, Dept Radiol, Salt Lake City, UT 84132 USA Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Kholmovski, Eugene G.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Utah, Sch Med, Dept Radiol, Salt Lake City, UT 84132 USA Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Oakes, Robert S.
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h-index: 0
机构:
Univ Utah, Dept Bioengn, Salt Lake City, UT 84132 USA Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Blauer, Joshua J. E.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Utah, Dept Bioengn, Salt Lake City, UT 84132 USA Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Daccarett, Marcos
论文数: 0 引用数: 0
h-index: 0
机构: Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Segerson, Nathan
论文数: 0 引用数: 0
h-index: 0
机构: Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Airey, Kelly J.
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h-index: 0
机构: Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Akoum, Nazem
论文数: 0 引用数: 0
h-index: 0
机构: Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Fish, Eric
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Utah, Dept Bioengn, Salt Lake City, UT 84132 USA Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Badger, Troy J.
论文数: 0 引用数: 0
h-index: 0
机构: Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

DiBella, Edward V. R.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Utah, Sch Med, Dept Radiol, Salt Lake City, UT 84132 USA
Univ Utah, Dept Bioengn, Salt Lake City, UT 84132 USA Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Parker, Dennis
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Utah, Sch Med, Dept Radiol, Salt Lake City, UT 84132 USA
Univ Utah, Dept Bioengn, Salt Lake City, UT 84132 USA Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

MacLeod, Rob S.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Utah, Dept Bioengn, Salt Lake City, UT 84132 USA Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA

Marrouche, Nassir F.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA Univ Utah, Sch Med, Hlth Sci Ctr, Div Cardiol,Attrial Fibrillat Program, Salt Lake City, UT 84132 USA