Application of Ramucirumab Exposure-Response Modeling to Support Dose Selection for Post Marketing Studies in Patients with Gastric Cancer

被引:0
|
作者
O'Brien, Lisa [1 ]
Gao, Ling [2 ]
Heathman, Michael [1 ]
机构
[1] Eli Lilly & Co, Indianapolis, IN 46285 USA
[2] Eli Lilly & Co, Bridgewater, NJ USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
M-36
引用
收藏
页码:S28 / S28
页数:1
相关论文
共 50 条
  • [41] Exposure-Response Modeling of Phase 1 Data to Inform Phase 2 Dose Selection: a Case Study Using AMG 827 in Psoriasis
    Salinger, David H.
    Martin, David A.
    Gibbs, Megan
    JOURNAL OF CLINICAL PHARMACOLOGY, 2011, 51 (09): : 1364 - 1364
  • [42] Exposure-response analyses for optimal therapeutic dose selection of ABBV-383 in patients with relapsed/refractory multiple myeloma (RRMM)
    Polepally, Akshanth
    Badillo, Jesus D.
    de Almeida, Carla Biesdorf
    Voorhees, Peter M.
    D'Souza, Anita
    Kumar, Shaji
    Bueno, Orlando Felix
    Rosenberg, Tanya
    Pothacamury, Rajvineeth Kumar
    Talati, Chetasi
    Menon, Rajeev
    Mensing, Sven
    Engelhardt, Benjamin
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [43] Selinexor population pharmacokinetic and exposure-response analyses to support dose optimization in patients with diffuse large B-cell lymphoma
    Xu, Hongmei
    Li, Hanbin
    Wada, Russ
    Bader, Justin C.
    Tang, Shijie
    Shah, Jatin
    Shacham, Sharon
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2021, 88 (01) : 69 - 79
  • [44] Pharmacokinetic and exposure-response analysis of pertuzumab in patients with HER2-positive metastatic gastric or gastroesophageal junction cancer
    Kirschbrown, Whitney P.
    Wang, Bei
    Nijem, Ihsan
    Ohtsu, Atsushi
    Hoff, Paulo M.
    Shah, Manish A.
    Shen, Lin
    Kang, Yoon-Koo
    Alsina, Maria
    Girish, Sandhya
    Garg, Amit
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2019, 84 (03) : 539 - 550
  • [45] Dose adjustments and exposure-response associated with selpercatinib in patients with advanced non-small cell lung cancer (NSCLC)
    Park, Keunchil
    Arriola, Edurne
    Perol, Maurice
    Zhou, Caicun
    Goto, Koichi
    Loong, Herbert
    Barker, Scott S.
    Massey, Ashish
    Peterson, Patrick M.
    Liu, Dan
    Akil, Ayman
    Solomon, Ben J.
    Pruthi, Aarohan
    ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2024, 20 : 140 - 140
  • [46] Analysis of exposure-response of CI-945 in patients with epilepsy: application of novel mixed hidden Markov modeling methodology
    Delattre, Maud
    Savic, Radojka M.
    Miller, Raymond
    Karlsson, Mats O.
    Lavielle, Marc
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2012, 39 (03) : 263 - 271
  • [47] Exposure-Response Analyses and Disease Modeling for Selection and Confirmation of Optimal Dosing Regimen of Isatuximab in Combination Treatment in Patients with Multiple Myeloma
    Rachedi, Fatiha
    Koiwai, Kimiko
    Gaudel-Dedieu, Nadia
    Sebastien, Bernard
    Thai, Hoai-Thu
    El-Cheikh, Raouf
    Brillac, Claire
    Fau, Jean Baptiste
    Nguyen, Laurent
    Liu, Li
    Campana, Frank
    van de Velde, Helgi
    Veyrat-Follet, Christine
    Semiond, Dorothee
    BLOOD, 2019, 134
  • [48] Exposure-response modeling for extrapolation from adult to pediatric patients who differ with respect to prognostic factors: Application to everolimus
    Dumortier, Thomas
    Heimann, Gunter
    Fink, Martin
    CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2021, 10 (06): : 589 - 598
  • [49] EXPOSURE-RESPONSE ANALYSES TO SUPPORT DOSE SELECTION OF BMS-936557, A MONOCLONAL ANTIBODY TO IP-10, FOR A PHASE 2B STUDY IN PATIENTS WITH ULCERATIVE COLITIS
    Tao, X.
    Xu, L.
    Shi, R.
    Luo, A.
    Shen, J.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2011, 89 : S62 - S63
  • [50] Population PK-PD and Exposure-Response Modeling and Simulation to Support Dose Recommendation of Xolair in Chronic Idiopathic Urticaria/Chronic Spontaneous Urticaria
    Zheng, Yanan
    Le, Kha
    Wada, Russ
    Jin, Jin
    Putnam, Wendy
    Rosen, Karin
    Chen, Hubert
    Hsieh, Hsin-Ju
    Lowe, Philip J.
    Visich, Jennifer
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2014, 41 : S32 - S33