Targeting PP2A to overcome enzalutamide resistance in AR plus breast tumors

被引：1
|
作者：
Cristobal, Ion [1 ]
Torrejon, Blanca [1 ]
Pedregal, Manuel [1 ]
Rojo, Federico [2 ]
Garcia-Foncillas, Jesus [1 ]
机构：
[1] Univ Hosp Fdn Jimenez Diaz, IIS Fdn Jimenez Diaz UAM, Translat Oncol Div, Oncohlth Inst, Madrid, Spain
[2] Univ Hosp Fdn Jimenez Diaz, IIS Fdn Jimenez Diaz UAM, Pathol Dept, Madrid, Spain
来源：
ENDOCRINE-RELATED CANCER | 2017年 / 24卷 / 01期
关键词：
ANDROGEN RECEPTOR; PROSTATE-CANCER; INHIBITOR; EXPRESSION; CELLS; AXIS;
D O I：
10.1530/ERC-16-0444
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：L5 / L6
页数：2
相关论文
共 50 条
  • [1] Targeting DNMTs to Overcome Enzalutamide Resistance in Prostate Cancer
    Farah, Elia
    Zhang, Zhuangzhuang
    Utturkar, Sagar M.
    Liu, Jinpeng
    Ratliff, Timothy L.
    Liu, Xiaoqi
    MOLECULAR CANCER THERAPEUTICS, 2022, 21 (01) : 193 - 205
  • [2] Targeting PP2A for cancer therapeutic modulation
    Ronk, Halle
    Rosenblum, Jared S.
    Kung, Timothy
    Zhuang, Zhengping
    CANCER BIOLOGY & MEDICINE, 2022, 19 (10) : 1428 - 1439
  • [3] PP2A as the Main Node of Therapeutic Strategies and Resistance Reversal in Triple-Negative Breast Cancer
    Zhao, Henan
    Li, Duojiao
    Zhang, Baojing
    Qi, Yan
    Diao, Yunpeng
    Zhen, Yuhong
    Shu, Xiaohong
    MOLECULES, 2017, 22 (12):
  • [4] PP2A regulates signaling through hormonal receptors in breast cancer with important therapeutic implications
    Cristobal, Ion
    Torrejon, Blanca
    Martinez-Useros, Javier
    Madoz-Gurpide, Juan
    Rojo, Federico
    Garcia-Foncillas, Jesus
    BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2017, 1868 (02): : 435 - 438
  • [5] Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance?
    Williams, Michelle M.
    Cook, Rebecca S.
    ONCOTARGET, 2015, 6 (06) : 3519 - 3530
  • [6] Targeting of PP2A enzymes by viral proteins and cancer signalling
    Godet, Angelique N.
    Guergnon, Julien
    Galioot, Amandine
    Falanga, Pierre-Barthelemy
    Colle, Jean-Herve
    Cayla, Xavier
    Garcia, Alphonse
    M S-MEDECINE SCIENCES, 2011, 27 (12): : 1106 - 1111
  • [7] Targeting Breast Cancer Stem Cells to Overcome Treatment Resistance
    Palomeras, Sonia
    Ruiz-Martinez, Santiago
    Puig, Teresa
    MOLECULES, 2018, 23 (09):
  • [8] The Pivotal Role of Protein Phosphatase 2A (PP2A) in Brain Tumors
    Cucinotta, Laura
    Filippone, Alessia
    Casili, Giovanna
    Lanza, Marika
    Bova, Valentina
    Capra, Anna Paola
    Giuffrida, Raffaella
    Colarossi, Cristina
    Sciacca, Dorotea
    Paterniti, Irene
    Cuzzocrea, Salvatore
    Campolo, Michela
    Esposito, Emanuela
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (24)
  • [9] Targeting Inhibitors of the Tumor Suppressor PP2A for the Treatment of Pancreatic Cancer
    Farrell, Amy S.
    Allen-Petersen, Brittany
    Daniel, Colin J.
    Wang, Xiaoyan
    Wang, Zhiping
    Rodriguez, Sarah
    Impey, Soren
    Oddo, Jessica
    Vitek, Michael P.
    Lopez, Charles
    Christensen, Dale J.
    Sheppard, Brett
    Sears, Rosalie C.
    MOLECULAR CANCER RESEARCH, 2014, 12 (06) : 924 - 939
  • [10] Unique targeting of androgen-dependent and -independent AR signaling in prostate cancer to overcome androgen resistance
    Lim, Syer C.
    Jansson, Patric J.
    Assinder, Stephen J.
    Maleki, Sanaz
    Richardson, Des R.
    Kovacevic, Zaklina
    FASEB JOURNAL, 2020, 34 (09): : 11511 - 11528
12345