Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies

被引：512

作者：

Nasica-Labouze, Jessica ^{[1
]}

Nguyen, Phuong H. ^{[1
]}

Sterpone, Fabio ^{[1
]}

Berthoumieu, Olivia ^{[2
]}

Buchete, Nicolae-Viorel ^{[3
,4
]}

Cote, Sebastien ^{[5
,6
]}

De Simone, Alfonso ^{[7
]}

Doig, Andrew J. ^{[8
]}

Faller, Peter ^{[2
]}

Garcia, Angel ^{[9
]}

Laio, Alessandro ^{[11
]}

Li, Mai Suan ^{[12
,13
]}

Melchionna, Simone ^{[14
]}

Mousseau, Normand ^{[3
,4
]}

Mu, Yuguang ^{[15
]}

Paravastu, Anant ^{[16
,17
]}

Pasquali, Samuela ^{[1
]}

Rosenman, David J. ^{[10
]}

Strodel, Birgit ^{[18
]}

Tarus, Bogdan ^{[1
]}

Viles, John H. ^{[19
]}

Zhang, Tong ^{[1
,15
]}

Wang, Chunyu ^{[16
]}

Derreumaux, Philippe ^{[1
,20
]}

机构：

[1] Sorbonne Paris Cite, Univ Paris Diderot, CNRS, Lab Biochim Theor,IBPC,UPR9080, F-75005 Paris, France

[2] Univ Toulouse 3, Univ Toulouse, CNRS, LCC,INPT, F-31077 Toulouse 4, France

[3] Univ Coll Dublin, Sch Phys, Dublin 4, Ireland

[4] Univ Coll Dublin, Complex & Adapt Syst Lab, Dublin 4, Ireland

[5] Univ Montreal, Dept Phys, Montreal, PQ H3C 3T5, Canada

[6] Univ Montreal, Grp Rech Prot Membranaires GEPROM, Montreal, PQ H3C 3T5, Canada

[7] Univ London Imperial Coll Sci Technol & Med, Dept Life Sci, London SW7 2AZ, England

[8] Univ Manchester, Manchester Inst Biotechnol, Manchester M1 7DN, Lancs, England

[9] Rensselaer Polytech Inst, Dept Phys Appl Phys & Astron, Troy, NY 12180 USA

[10] Rensselaer Polytech Inst, Dept Biol, Troy, NY 12180 USA

[11] Int Sch Adv Studies SISSA, I-34136 Trieste, Italy

[12] Polish Acad Sci, Inst Phys, PL-02668 Warsaw, Poland

[13] Inst Computat Sci & Technol, Tan Chanh Hiep Ward, Ho Chi Minh City, Vietnam

[14] CNR, IPCF, I-00185 Rome, Italy

[15] Nanyang Technol Univ, Sch Biol Sci, Singapore 637551, Singapore

[16] FAMU FSU, Coll Engn, Dept Chem & Biomed Engn, Tallahassee, FL 32310 USA

[17] Natl High Magnet Field Lab, Tallahassee, FL 32310 USA

[18] Forschungszentrum Julich GmbH, Inst Complex Syst Struct Biochem ICS6, D-52425 Julich, Germany

[19] Queen Mary Univ London, Sch Biol & Chem Sci, London E1 4NS, England

[20] Inst Univ France, F-75005 Paris, France

来源：

CHEMICAL REVIEWS | 2015年 / 115卷 / 09期

基金：

欧洲研究理事会; 美国国家科学基金会; 英国生物技术与生命科学研究理事会;

关键词：

SOLID-STATE NMR; MOLECULAR-DYNAMICS SIMULATIONS; CELLULAR PRION PROTEIN; HUMAN SERUM-ALBUMIN; INTRINSICALLY DISORDERED PROTEIN; METABOTROPIC GLUTAMATE-RECEPTOR; ATOMIC-LEVEL CHARACTERIZATION; CENTRAL-NERVOUS-SYSTEM; FREE-ENERGY LANDSCAPES; RAY FIBER DIFFRACTION;

D O I：

10.1021/cr500638n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：3518 / 3563

页数：46

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