Neonatal Jaundice in Low- and Middle-Income Countries: Lessons and Future Directions from the 2015 Don Ostrow Trieste Yellow Retreat

被引：111

作者：

Greco, Chiara ^{[1
]}

Arnolda, Gaston ^{[10
]}

Boo, Nem-Yun ^{[3
]}

Iskander, Iman F. ^{[4
]}

Okolo, Angela A. ^{[5
]}

Rohsiswatmo, Rinawati ^{[6
]}

Shapiro, Steven M. ^{[7
]}

Watchko, Jon ^{[8
]}

Wennberg, Richard P. ^{[1
,9
]}

Tiribelli, Claudio ^{[1
,2
]}

Zabetta, Carlos D. Coda ^{[1
]}

机构：

[1] Bilimetrix, Basovizza, TS, Italy

[2] Fdn Italiana Fegato, AREA Sci Pk,Campus Basovizza, IT-34149 Trieste, Italy

[3] Univ Tunku Abdul Rahman, Dept Populat Med, Petaling Jaya, Malaysia

[4] Cairo Univ, Children Hosp, Cairo, Egypt

[5] Fed Med Ctr, Asaba, Nigeria

[6] Univ Indonesia, Cipto Mangunkusumo Hosp, Dept Child Hlth, Neonatol Div, Jakarta, Indonesia

[7] Childrens Mercy Hosp & Clin, Kansas City, MO USA

[8] Univ Pittsburgh, Sch Med, Dept Pediat, Div Newborn Med, Pittsburgh, PA 15261 USA

[9] Univ Washington, Dept Pediat, Seattle, WA 98195 USA

[10] Thr Networks, Oakland, CA USA

来源：

NEONATOLOGY | 2016年 / 110卷 / 03期

基金：

比尔及梅琳达.盖茨基金会;

关键词：

Neonatal jaundice; Severe hyperbilirubinemia; Acute bilirubin encephalopathy; Kernicterus; Low-; and middle-income countries; EXTREME HYPERBILIRUBINEMIA; EXCHANGE-TRANSFUSION; NEWBORN JAUNDICE; RISK-FACTORS; BILIRUBIN; CARE; PHOTOTHERAPY; KERNICTERUS; INFANTS; NEUROTOXICITY;

D O I：

10.1159/000445708

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Severe neonatal hyperbilirubinemia, defined as total serum bilirubin (TSB) >= 20 mg/dl, is associated with a higher risk of permanent neurological sequelae and death. Jaundice can and should be promptly diagnosed and treated. Reliable methods for TSB assay are not always readily available, particularly in low- and middle-income countries, making the true incidence of severe neonatal jaundice (NNJ) difficult to estimate. To gather a more comprehensive picture, a symposium addressing NNJ worldwide was organized during the 2015 Don Ostrow Trieste Yellow Retreat. Data collected by several researchers in different regions of the world were presented and differences/similarities discussed. This report points out the need for: (1) a coordinated worldwide effort to define the burden and the causes of severe NNJ and its consequences; (2) aggressive educational programs for families and health personnel to facilitate timely care-seeking, and (3) accurate diagnostics and effective phototherapy. (C) 2016 S. Karger AG, Basel

引用

页码：172 / 180

页数：9

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