Cerebral venous sinus thrombosis-associated hemorrhage in vaccine-induced immune thrombotic thrombocytopenia: Catastrophic outcome if delayed diagnosis and treatment

被引：0

作者：

Lam, Chee-Tat ^{[1
]}

Lin, Kuan-Yu ^{[2
]}

Kao, Ming-Chien ^{[1
]}

Tsai, Ming-Cheng ^{[1
,3
]}

机构：

[1] Fu Jen Catholic Univ, Dept Neurosurg, Shin Kong Wu Ho Su Mem Hosp, New Taipei, Taiwan

[2] Fu Jen Catholic Univ, Dept Neurol, Shin Kong Wu Ho Su Mem Hosp, New Taipei, Taiwan

[3] Fu Jen Catholic Univ, Coll Med, Sch Med, New Taipei, Taiwan

来源：

FORMOSAN JOURNAL OF SURGERY | 2022年 / 55卷 / 04期

关键词：

Anti-platelet factor 4 antibodies; cerebral venous thrombosis; vaccine-induced immune thrombotic thrombocytopenia;

D O I：

10.4103/fjs.fjs_236_21

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The authors reported the clinical course of a 58-year-old female suffering from cerebral venous sinus thrombosis associated with hemorrhage after the ChAdOx1 nCov-19 vaccination. Emergent decompressive craniectomy was performed, and aggressive blood transfusion was given. Nevertheless, progressive intracerebral hemorrhage and thrombocytopenia developed. A delayed diagnosis was made on a rare complication of vaccine-induced immune thrombotic thrombocytopenia (VITT) with a positive result of anti-platelet factor 4 antibodies (PF4 Ab). The patient died 4 days postoperative due to brainstem failure.

引用

页码：158 / 160

页数：3

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