Study on Cephalosporins with Terahertz Time-Domain Spectroscopy Technique

被引：1

作者：

Zhang Man ^{[1
]}

Zhu Si-yuan ^{[1
]}

Li Qing-mei ^{[1
]}

Shen Jing-ling ^{[1
]}

机构：

[1] Capital Normal Univ, Dept Phys, Beijing Key Lab Terahertz Spect & Imaging, Key Lab Terahertz Optoelect,Minist Educ, Beijing 100048, Peoples R China

来源：

SPECTROSCOPY AND SPECTRAL ANALYSIS | 2013年 / 33卷 / 02期

关键词：

Cephalosporins; Terahertz time-domain spectroscopy technique; Absorption; Index of refractive; Content calculation of cefixime; PULSED SPECTROSCOPY;

D O I：

10.3964/j.issn.1000-0593(2013)02-0330-04

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Terahertz Time-Domain Spectroscopy (THz-TDS) technique has a wide range of applications in substances identification and quantitative analysis. In the present paper, we report absorption spectra and index of refraction of 14 kinds of pure cephalosporins in 0.2 similar to 2.6 THz, in which eight kinds have apparent absorption peaks, while the others have different index of refraction. Based on these results, different kinds of antibiotics can be identified. Besides, according to THz absorption spectra of both pure sample and real pills we calculated the contents of cefixime in the two pills produced by two manufacturers. Compared with the contents marked on the package, relative errors are 9.38% and 0.92%, respectively. The results manifest that THz-TDS technique is reliable and promising in medicine detection.

引用

页码：330 / 333

页数：4

共 14 条

[1]

Abraham E, 2010, APPL PHYS A, V10, P1007

[2] Terahertz pulsed spectroscopy of freshly excised human breast cancer [J].

Ashworth, Philip C. ;

Pickwell-MacPherson, Emma ;

Provenzano, Elena ;

Pinder, Sarah E. ;

Purushotham, Anand D. ;

Pepper, Michael ;

Wallace, Vincent P. .

OPTICS EXPRESS, 2009, 17 (15) :12444-12454

[3] Material parameter estimation with terahertz time-domain spectroscopy [J].

Dorney, TD ;

Baraniuk, RG ;

Mittleman, DM .

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 2001, 18 (07) :1562-1571

[4]

JIANG DJ, 2007, P SOC PHOTO-OPT INS, V6840, P1

[5]

Jin B., 2010, TERAHERTZ SCI TECHNO, V3, P192

[6] Identification of illicit drugs by using SOM neural networks [J].

Liang, Meiyan ;

Shen, Jingling ;

Wang, Guangqin .

JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2008, 41 (13)

[7]

Lionel Duvillaret, 1996, IEEE J SEL TOP QUANT, V2, P793

[8]

Lionel Duvillaret, 1998, APP OPTI, V38, P409

[9]

Liu XH, 2010, PROG CHEM, V22, P2191

[10] Pulsed terahertz spectroscopy of DNA, bovine serum albumin and collagen between 0.1 and 2.0 THz [J].

Markelz, AG ;

Roitberg, A ;

Heilweil, EJ .

CHEMICAL PHYSICS LETTERS, 2000, 320 (1-2) :42-48

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