Amino acid racemization and the preservation of ancient DNA

被引：286

作者：

Poinar, HN ^{[1
]}

Hoss, M ^{[1
]}

Bada, JL ^{[1
]}

Paabo, S ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO,SCRIPPS INST OCEANOG,LA JOLLA,CA 92093

来源：

SCIENCE | 1996年 / 272卷 / 5263期

关键词：

D O I：

10.1126/science.272.5263.864

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The extent of racemization of aspartic acid, alanine, and leucine provides criteria for assessing whether ancient tissue samples contain endogenous DNA, In samples in which the D/L ratio of aspartic acid exceeds 0.08, ancient DNA sequences could not be retrieved. Paleontological finds from which DNA sequences purportedly millions of years old have been reported show extensive racemization, and the amino acids present are mainly contaminates, An exception is the amino acids in some insects preserved in amber.

引用

页码：864 / 866

页数：3

共 39 条

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