Nanostructured bicontinuous cubic lipid self-assembly materials as matrices for protein encapsulation

被引：105

作者：

Conn, Charlotte E. ^{[1
]}

Drummond, Calum J. ^{[1
]}

机构：

[1] CSIRO Mat Sci & Engn CMSE, Clayton, Vic 3169, Australia

来源：

SOFT MATTER | 2013年 / 9卷 / 13期

基金：

澳大利亚研究理事会;

关键词：

X-RAY-DIFFRACTION; LYOTROPIC LIQUID-CRYSTAL; DRUG-DELIVERY SYSTEMS; MEMBRANE-PROTEINS; CYTOCHROME-C; MONOOLEIN/WATER SYSTEM; WATER PHASES; KINASE-C; TRANSMEMBRANE PEPTIDES; ALPHA-CHYMOTRYPSIN;

D O I：

10.1039/c3sm27743g

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We review the use of bicontinuous cubic amphiphile self-assembly materials for protein encapsulation. The unique amphiphilic nature of bicontinuous cubic lipidic phases make them an ideal medium for the encapsulation of soluble, peripheral, and integral membrane proteins. Current and prospective applications for such systems include drug delivery, membrane protein crystallisation, biosensors and biofuel cells. We focus on the impact of the incorporated protein on the structure of the cubic phase, which has a knock-on effect on performance for many end-applications.

引用

页码：3449 / 3464

页数：16

共 125 条

[1] CUBIC MEMBRANES: THE MISSING DIMENSION OF CELL MEMBRANE ORGANIZATION [J].

Almsherqi, Zakaria A. ;

Landh, Tomas ;

Kohlwein, Sepp D. ;

Deng, Yuru .

INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 274, 2009, 274 :275-342

[2] Templating effects of lyotropic liquid crystals in the encapsulation of amyloid fibrils and their stimuli-responsive magnetic behavior [J].

Amar-Yuli, Idit ;

Adamcik, Jozef ;

Lara, Cecile ;

Bolisetty, Sreenath ;

Vallooran, Jijo J. ;

Mezzenga, Raffaele .

SOFT MATTER, 2011, 7 (07) :3348-3357

[3] Protein nanodomain patterns in lipidic bicontinuous cubic phases [J].

Angelov, B .

MODERN PHYSICS LETTERS B, 2002, 16 (07) :225-230

[4] Protein-Containing PEGylated Cubosomic Particles: Freeze-Fracture Electron Microscopy and Synchrotron Radiation Circular Dichroism Study [J].

Angelov, Borislav ;

Angeova, Angelina ;

Papahadjopoulos-Sternberg, Brigitte ;

Hoffmann, Soren V. ;

Nicolas, Valerie ;

Lesieur, Sylviane .

JOURNAL OF PHYSICAL CHEMISTRY B, 2012, 116 (26) :7676-7686

[5] Interaction of the peptide antibiotic alamethicin with bilayer- and non-bilayer-forming lipids: Influence of increasing alamethicin concentration on the lipids supramolecular structures [J].

Angelova, A ;

Ionov, R ;

Koch, MHJ ;

Rapp, G .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2000, 378 (01) :93-106

[6] Proteocubosomes: Nanoporous vehicles with tertiary organized fluid interfaces [J].

Angelova, A ;

Angelov, B ;

Papahadjopoulos-Sternberg, B ;

Ollivon, M ;

Bourgaux, C .

LANGMUIR, 2005, 21 (09) :4138-4143

[7] Structural organization of proteocubosome carriers involving medium- and large-size proteins [J].

Angelova, A ;

Angelov, B ;

Papahadjopoulos-Sternberg, B ;

Ollivon, M ;

Bourgaux, C .

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2005, 15 (01) :108-112

[8] Lipid cubic phases as stable nanochannel network structures for protein biochip development: X-ray diffraction study [J].

Angelova, A ;

Ollivon, M ;

Campitelli, A ;

Bourgaux, C .

LANGMUIR, 2003, 19 (17) :6928-6935

[9] Small-Angle X-ray Scattering Investigations of Biomolecular Confinement, Loading, and Release from Liquid-Crystalline Nanochannel Assemblies [J].

Angelova, Angelina ;

Angelov, Borislav ;

Garamus, Vasil M. ;

Couvreur, Patrick ;

Lesieur, Sylviane .

JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2012, 3 (03) :445-457

[10] Self-Assembled Multicompartment Liquid Crystalline Lipid Carriers for Protein, Peptide, and Nucleic Acid Drug Delivery [J].

Angelova, Angelina ;

Angelov, Borislav ;

Mutafchieva, Rada ;

Lesieur, Sylviane ;

Couvreur, Patrick .

ACCOUNTS OF CHEMICAL RESEARCH, 2011, 44 (02) :147-156

← 1 2 3 4 5 6 7 8 9 10 →