Drug-related killings: A case of mistaken identity

被引：42

作者：

Karran, P ^{[1
]}

Bignami, M ^{[1
]}

机构：

[1] IST SUPER SANITA,I-00161 ROME,ITALY

来源：

CHEMISTRY & BIOLOGY | 1996年 / 3卷 / 11期

关键词：

D O I：

10.1016/S1074-5521(96)90175-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Abortive attempts at DNA repair can contribute to the effects of DNA damage inflicted by cytotoxic drugs. DNA methylation damage, 6-thioguanine and cisplatin adducts all owe their cytotoxicity in part to the intervention of DNA mismatch repair.

引用

页码：875 / 879

页数：5

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