From words to literature in structural proteomics

被引：344
作者：
Sali, A [1 ]
Glaeser, R
Earnest, T
Baumeister, W
机构：
[1] Univ Calif San Francisco, Dept Biopharmaceut Sci, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Pharmaceut Chem, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Calif Inst Quantitat Biomed Res, San Francisco, CA 94143 USA
[4] Univ Calif Berkeley, Dept Mol & Cell Biol, Stanley Donner ASU, Berkeley, CA 94720 USA
[5] Univ Calif Berkeley, Lawrence Berkeley Lab, Phys Biosci Div, Berkeley Ctr Struct Biol, Berkeley, CA 94720 USA
[6] Max Planck Inst Biochem, Dept Biol Struct, D-82152 Martinsried, Germany
来源：
NATURE | 2003年 / 422卷 / 6928期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1038/nature01513
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Technical advances on several frontiers have expanded the applicability of existing methods in structural biology and helped close the resolution gaps between them. As a result, we are now poised to integrate structural information gathered at multiple levels of the biological hierarchy - from atoms to cells - into a common framework. The goal is a comprehensive description of the multitude of interactions between molecular entities, which in turn is a prerequisite for the discovery of general structural principles that underlie all cellular processes.
引用
收藏
页码：216 / 225
页数：10
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共 100 条
  • [1] Proteomics: The society of proteins
    Abbott, A
    [J]. NATURE, 2002, 417 (6892) : 894 - 896
  • [2] Automation of X-ray crystallography
    Abola, E
    Kuhn, P
    Earnest, T
    Stevens, RC
    [J]. NATURE STRUCTURAL BIOLOGY, 2000, 7 (Suppl 11) : 973 - 977
  • [3] The cell as a collection of protein machines: Preparing the next generation of molecular biologists
    Alberts, B
    [J]. CELL, 1998, 92 (03) : 291 - 294
  • [4] The third dimension for protein interactions and complexes
    Aloy, P
    Russell, RB
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 2002, 27 (12) : 633 - 638
  • [5] Potential artefacts in protein-interaction networks
    Aloy, P
    Russell, RB
    [J]. FEBS LETTERS, 2002, 530 (1-3) : 253 - 254
  • [6] A complex prediction:: three-dimensional model of the yeast exosome
    Aloy, P
    Ciccarelli, FD
    Leutwein, C
    Gavin, AC
    Superti-Furga, G
    Bork, P
    Böttcher, B
    Russell, RB
    [J]. EMBO REPORTS, 2002, 3 (07) : 628 - 635
  • [7] Interrogating protein interaction networks through structural biology
    Aloy, P
    Russell, RB
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (09) : 5896 - 5901
  • [8] [Anonymous], 1996, 3 DIMENSIONAL ELECT
  • [9] Protein structure prediction and structural genomics
    Baker, D
    Sali, A
    [J]. SCIENCE, 2001, 294 (5540) : 93 - 96
  • [10] The complete atomic structure of the large ribosomal subunit at 2.4 Å resolution
    Ban, N
    Nissen, P
    Hansen, J
    Moore, PB
    Steitz, TA
    [J]. SCIENCE, 2000, 289 (5481) : 905 - 920
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