Cerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient

被引:6
作者
Bittner, Aitomi [1 ,2 ,3 ,4 ]
Radke, Josefine [2 ,3 ,4 ,5 ,6 ,7 ]
Eurich, Dennis [2 ,3 ,4 ,8 ]
Wiener, Edzard [9 ]
Denker, Sophy [2 ,3 ,4 ]
Anagnostopoulos, Ioannis [10 ]
Na, Il-Kang [1 ,2 ,3 ,4 ,5 ,11 ,12 ]
Heppner, Frank L. [2 ,3 ,4 ,5 ,7 ,13 ,14 ]
Bullinger, Lars [1 ,2 ,3 ,4 ,5 ,6 ,7 ,15 ]
Schmitt, Clemens A. [1 ,2 ,3 ,4 ,6 ,15 ,16 ]
机构
[1] Charit Univ Med Berlin, Dept Hematol Oncol & Tumor Immunol, Berlin, Germany
[2] Free Univ Berlin, Berlin, Germany
[3] Humboldt Univ, Berlin, Germany
[4] Berlin Inst Hlth, Berlin, Germany
[5] Berlin Inst Hlth BIH, Berlin, Germany
[6] German Canc Consortium DKTK, Berlin, Germany
[7] Charit Univ Med Berlin, Dept Neuropathol, Berlin, Germany
[8] Charit Univ Med Berlin, Dept Surg, Berlin, Germany
[9] Charit Univ Med Berlin, Inst Neuroradiol, Berlin, Germany
[10] Univ Wurzburg, Inst Pathol, Wurzburg, Germany
[11] Expt & Clin Res Ctr ECRC, Berlin, Germany
[12] BIH Ctr Regenerat Therapies, Berlin, Germany
[13] NeuroCure, Cluster Excellence, Berlin, Germany
[14] German Ctr Neurodegenerat Dis DZNE, Berlin, Germany
[15] Helmholtz Assoc, Max Delbruck Ctr Mol Med, Berlin, Germany
[16] Johannes Kepler Univ Linz, Kepler Univ Hosp, Dept Hematol & Oncol, Linz, Austria
关键词
D O I
10.1080/10428194.2021.1889537
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:2026 / 2029
页数:4
相关论文
共 13 条
[1]   Checkpoint inhibitor therapy for cancer in solid organ transplantation recipients: an institutional experience and a systematic review of the literature [J].
Abdel-Wahab, Noha ;
Safa, Houssein ;
Abudayyeh, Ala ;
Johnson, Daniel H. ;
Van Anh Trinh ;
Zobniw, Chrystia M. ;
Lin, Heather ;
Wong, Michael K. ;
Abdelrahim, Maen ;
Gaber, A. Osama ;
Suarez-Almazor, Maria E. ;
Diab, Adi .
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
[2]   Successful Treatment of Disseminated Hepatocellular Carcinoma After Liver Transplantation With Nivolumab [J].
Amjad, Waseem ;
Kotiah, Sandy ;
Gupta, Ankur ;
Morris, Michael ;
Liu, Li ;
Thuluvath, Paul J. .
JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY, 2020, 10 (02) :185-187
[3]   Risk factors and incidence of de novo malignancy in liver transplant recipients: a systematic review [J].
Chak, Eric ;
Saab, Sammy .
LIVER INTERNATIONAL, 2010, 30 (09) :1247-1258
[4]   Targetable genetic features of primary testicular and primary central nervous system lymphomas [J].
Chapuy, Bjoern ;
Roemer, Margaretha G. M. ;
Stewart, Chip ;
Tan, Yuxiang ;
Abo, Ryan P. ;
Zhang, Liye ;
Dunford, Andrew J. ;
Meredith, David M. ;
Thorner, Aaron R. ;
Jordanova, Ekaterina S. ;
Liu, Gang ;
Feuerhake, Friedrich ;
Ducar, Matthew D. ;
Illerhaus, Gerald ;
Gusenleitner, Daniel ;
Linden, Erica A. ;
Sun, Heather H. ;
Homer, Heather ;
Aono, Miyuki ;
Pinkus, Geraldine S. ;
Ligon, Azra H. ;
Ligon, Keith L. ;
Ferry, Judith A. ;
Freeman, Gordon J. ;
van Hummelen, Paul ;
Golub, Todd R. ;
Getz, Gad ;
Rodig, Scott J. ;
de Jong, Daphne ;
Monti, Stefano ;
Shipp, Margaret A. .
BLOOD, 2016, 127 (07) :869-881
[5]   Immune checkpoint inhibitor therapy in solid organ transplant recipients: A patient-centered systematic review [J].
Fisher, Juliya ;
Zeitouni, Nathalie ;
Fan, Weijia ;
Samie, Faramarz H. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2020, 82 (06) :1490-1500
[6]   Constitutive AP-1 Activity and EBV Infection Induce PD-L1 in Hodgkin Lymphomas and Posttransplant Lymphoproliferative Disorders: Implications for Targeted Therapy [J].
Green, Michael R. ;
Rodig, Scott ;
Juszczynski, Przemyslaw ;
Ouyang, Jing ;
Sinha, Papiya ;
O'Donnell, Evan ;
Neuberg, Donna ;
Shipp, Margaret A. .
CLINICAL CANCER RESEARCH, 2012, 18 (06) :1611-1618
[7]   Hallmarks of Cancer: The Next Generation [J].
Hanahan, Douglas ;
Weinberg, Robert A. .
CELL, 2011, 144 (05) :646-674
[8]   Liver graft rejection following immune checkpoint inhibitors treatment: a review [J].
Hu, Bo ;
Yang, Xiao-Bo ;
Sang, Xin-Ting .
MEDICAL ONCOLOGY, 2019, 36 (11)
[9]   Post-transplant lymphoproliferative disorders following liver transplantation: Incidence, risk factors and survival [J].
Kremers, WK ;
Devarbhavi, HC ;
Wiesner, RH ;
Krom, RAF ;
Macon, WR ;
Habermann, TM .
AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (05) :1017-1024
[10]   On being less tolerant: Enhanced cancer immunosurveillance enabled by targeting checkpoints and agonists of T cell activation [J].
Lesokhin, Alexander M. ;
Callahan, Margaret K. ;
Postow, Michael A. ;
Wolchok, Jedd D. .
SCIENCE TRANSLATIONAL MEDICINE, 2015, 7 (280)