Mycosis fungoides:: a dermatological masquerader

被引:101
作者
Nashan, D.
Faulhaber, D.
Stander, S.
Luger, T. A.
Stadler, R.
机构
[1] Univ Munster, Dept Dermatol, D-4400 Munster, Germany
[2] Klinikum Minden, Dept Dermatol, Minden, Germany
[3] Univ Freiburg, Dept Dermatol, D-79104 Freiburg, Germany
关键词
clinical subtypes; differential diagnoses; mycosis fungoides; overview;
D O I
10.1111/j.1365-2133.2006.07526.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Mycosis fungoides (MF), a low-grade lymphoproliferative disorder, is the most common type of cutaneous T-cell lymphoma. Typically, neoplastic T cells localize to the skin and produce patches, plaques, tumours or erythroderma. Diagnosis of MF can be difficult due to highly variable presentations and the sometimes nonspecific nature of histological findings. Molecular biology has improved the diagnostic accuracy. Nevertheless, clinical experience is of substantial importance as MF can resemble a wide variety of skin diseases. We performed a literature review and found that MF can mimic > 50 different clinical entities. We present a structured framework of clinical variations of classical, unusual and distinct forms of MF. Distinct subforms such as ichthyotic MF, adnexotropic (including syringotropic and folliculotropic) MF, MF with follicular mucinosis, granulomatous MF with granulomatous slack skin and papuloerythroderma of Ofuji are delineated in more detail.
引用
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页码:1 / 10
页数:10
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