Finding the Differences in Capillaries of Taste Buds between Smokers and Non-Smokers Using the Convolutional Neural Networks

Featured Application The aim of this work is to strengthen patient awareness and willingness to quit smoking by presenting them with the diagnostic results obtained using the capillaroscopy-based deep-learning artificial intelligence methods. Taste function and condition may be a tool that exhibits a rapid deficit to impress the subject with an objectively measured effect of smoking on his/her own body, because smokers exhibit significantly lower taste sensitivity than non-smokers. This study proposed a visual method to measure capillaries of taste buds with capillaroscopy and classified the difference between smokers and non-smokers through convolutional neural networks (CNNs). The dataset was collected from 26 human subjects through the capillaroscopy with the low and high magnification directly; of which 13 were smokers, and the other 13 were non-smokers. The acquired dataset consisted of 2600 images. The results of gradient-weighted class activation mapping (grad-cam) enabled us to understand the difference in capillaries of taste buds between smokers and non-smokers. Through the results, it was found that CNNs gave us a good performance with 79% accuracy. It was discussed that there was a shortage of extracted features when the conventional methods such as structural similarity index (SSIM) and scale-invariant feature transform (SIFT) were used to classify.