SURVEY OF NONSUSCEPTIBLE NASOPHARYNGEAL STREPTOCOCCUS PNEUMONIAE ISOLATES IN CHILDREN ATTENDING DAY-CARE CENTERS IN BRAZIL

被引：20

作者：

Franco, Caritas M. ^{[3
]}

Andrade, Ana Lucia S. ^{[1
]}

Andrade, Joao G. ^{[2
]}

Almeida e Silva, Simonne ^{[1
]}

Oliveira, C. Renato M. ^{[1
]}

Pimenta, Fabiana C. ^{[4
]}

Lamaro-Cardoso, Juliana ^{[5
]}

Brandao, Angela P. ^{[6
]}

Almeida, Samanta C. G. ^{[6
]}

Calix, Juan J. ^{[7
,8
]}

Nahmi, Moon H. ^{[7
,8
]}

Brandileone, Maria-Cristina de Cunto ^{[6
]}

机构：

[1] Univ Fed Goias, Dept Community Hlth, Inst Trop Pathol & Publ Hlth, BR-74605050 Goiania, Go, Brazil

[2] Univ Fed Goias, Dept Trop Dis & Dermatol, Inst Trop Pathol & Publ Hlth, BR-74605050 Goiania, Go, Brazil

[3] Municipal Goiania, Secretariat Hlth, Goiania, Go, Brazil

[4] Ctr Dis Control & Prevent, Resp Dis Branch, Div Bacterial Dis, Atlanta, GA USA

[5] Univ Fed Goias, Dept Microbiol, Inst Trop Pathol & Publ Hlth, BR-74605050 Goiania, Go, Brazil

[6] Adolfo Lutz Inst, Bacteriol Branch, Sao Paulo, Brazil

[7] Univ Alabama, Dept Pathol, Birmingham, AL 35294 USA

[8] Univ Alabama, Dept Microbiol, Birmingham, AL 35294 USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2010年 / 29卷 / 01期

关键词：

pneumococcal carriage; pneumococcal serotypes; nasopharyngeal carriage; day care centers; vaccine coverage; nonsusceptible pneumococcal; SEROTYPES; CARRIAGE; COLONIZATION; VACCINES; DISEASE;

D O I：

10.1097/INF.0b013e3181af7e90

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A Survey of nasopharyngeal carriage of penicillin nonsusceptible pneumococcal (PNSp) isolates was conducted among 1192 children attending 62 day care centers in Brazil, where pneumococcal vaccination has not been routinely introduced. Nasopharyngeal pneumococcal carriage was detected in 686 (57.6%) infants, and 178 (25.9%) of them carried PNSp isolates. Being less than 24 months of age, hospitalization in the previous 3 months, and recurrent acute otitis media were independently associated with PNSp. Serotypes 14, 23F, 19A, 6A, 6B and 19F were the most common serotype isolated accounting for 80% of the PNSp. A high proportion (35/332) of non-(sero)typeable isolates was detected, 62.9% of them PNSp. Serotypes coverage projected for the pneumococcal conjugate vaccine (PCV) 13-valent vaccine (72%) was significantly higher compared with PCV7 (58.4%) and PCV 10-valent vaccine (59.3%).

引用

页码：77 / 79

页数：3

共 12 条

[1] Streptococcus pneumoniae colonisation:: the key to pneumococcal disease [J].

Bogaert, D ;

de Groot, R ;

Hermans, PWM .

LANCET INFECTIOUS DISEASES, 2004, 4 (03) :144-154

[2]

*CLIN LAB STAND I, 2007, M100S17 CLIN LAB S S

[3] Nasopharyngeal colonization in southern Israel with antibiotic-resistant pneumococci during the first 2 years of life: Relation to serotypes likely to be included in pneumococcal conjugate vaccines [J].

Dagan, R ;

Melamed, R ;

Muallem, M ;

Piglansky, L ;

Yagupsky, P .

JOURNAL OF INFECTIOUS DISEASES, 1996, 174 (06) :1352-1355

[4] Effect of the seven-valent conjugate pneumococcal vaccine on carriage and drug resistance of Streptococcus pneumoniae in healthy children attending day-care centers in Lisbon [J].

Frazao, N ;

Brito-Avô, A ;

Simas, C ;

Saldanha, J ;

Mato, R ;

Nunes, S ;

Sousa, NG ;

Carriço, JA ;

Almeida, JS ;

Santos-Sanches, I ;

de Lencastre, H .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2005, 24 (03) :243-252

[5] Nasopharyngeal carriage of Streptococcus pneumoniae in Gambian villagers [J].

Hill, Philip C. ;

Akisanya, Abiodun ;

Sankareh, Kawsu ;

Cheung, Yin Bun ;

Saaka, Mark ;

Lahai, George ;

Greenwood, Brian M. ;

Adegbola, Richard A. .

CLINICAL INFECTIOUS DISEASES, 2006, 43 (06) :673-679

[6] Serotypes of carriage and invasive isolates of Streptococcus pneumoniae in Brazilian children in the era of pneumococcal vaccines [J].

Laval, CB ;

de Andrade, ALSS ;

Pimenta, FC ;

de Andrade, JG ;

de Oliveira, RM ;

Silva, SA ;

de Lima, EC ;

Di Fabio, JL ;

Casagrande, ST ;

Brandileone, MCC .

CLINICAL MICROBIOLOGY AND INFECTION, 2006, 12 (01) :50-55

[7]

O'Brien KL, 2003, PEDIATR INFECT DIS J, V22, P133, DOI [10.1097/00006454-200302000-00009, 10.1097/00006454-200302000-00010]

[8]

*ORG PAN SAL, 2008, INF REG SIREVA 2 200

[9] Antimicrobial susceptibility and serotypes of nasopharyngeal Streptococcus pneumoniae in children with pneumonia and in children attending day-care centres in Fortaleza, Brazil [J].

Rey, LC ;

Wolf, B ;

Moreira, JLB ;

Milatovic, D ;

Verhoef, J ;

Farhat, CK .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2002, 20 (02) :86-92

[10] Identification, prevalence and population structure of non-typable Streptococcus pneumoniae in carriage samples isolated from preschoolers attending day-care centres [J].

Sá-Leao, R ;

Simoes, AS ;

Nunes, S ;

Sousa, NG ;

Frazao, N ;

de Lencastre, H .

MICROBIOLOGY-SGM, 2006, 152 :367-376

← 1 2 →