Evaluation of the national immunisation programme in the Netherlands:: immunity to diphtheria, tetanus, poliomyelitis, measles, mumps, rubella and Haemophilus influenzae type b

被引：24
作者：
de Melker, HE
van den Hof, S
Berbers, GAM
Conyn-van Spaendonck, MAE
机构：
[1] Natl Inst Publ Hlth & Environm, Dept Infect Dis Epidemiol, NL-3720 BA Bilthoven, Netherlands
[2] Natl Inst Publ Hlth & Environm, Lab Clin Vaccine Res, NL-3720 BA Bilthoven, Netherlands
来源：
VACCINE | 2003年 / 21卷 / 7-8期
关键词：
vaccine-preventable diseases; immunisation programmes; serumbank; seroepidemiology;
D O I：
10.1016/S0264-410X(02)00587-X
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The immunity to vaccine-preventable diseases included in the Dutch immunisation programme in the general population and among orthodox reformed individuals who refuse vaccination was assessed. The programme induces good protection. However, a large proportion of adults lacks diphtheria and tetanus immunity. Measles, mumps and rubella seroprevalence was somewhat lower among vaccinated compared to unvaccinated cohorts. The prevalence of HibPS antibodies declined during 2.5 years after the fourth vaccination. However, protection occurs also by memory immunity. Herd immunity is sufficient among the general population, but not among orthodox reformed individuals. Immunosurveillance is an efficient way to evaluate the effects of immunisation programmes and identify risk groups for infection. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：716 / 720
页数：5
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