Pressure changes in the human middle ear without opening the eustachian tube

被引:33
作者
Pau, Hans Wilhelm [1 ]
Sievert, Uwe [1 ]
Just, Tino [1 ]
Sade, Jacob [2 ,3 ]
机构
[1] Univ Rostock, ENT Dept, Sch Med, D-18057 Rostock, Germany
[2] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel
[3] Tel Aviv Univ, Bioengn Program, Tel Aviv, Israel
关键词
Middle ear pressure regulation; refraining from swallowing; non-opening of the eustachian tube; ME pressure decrease; trans-mucosal gas exchange; GAS-EXCHANGE; FLUORESCENCE ANGIOGRAPHY; TYMPANIC MEMBRANE; BLOOD; MODEL; RAT;
D O I
10.3109/00016480802570537
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Conclusion. By means of a direct, though non-invasive experiment on healthy humans we could demonstrate that middle ear (ME) pressure decreases when the eustachian tube (ET) does not open. Thus with a very simple method the basic theory of continuous gas loss from the ME into the circulation and the replenishment of the loss through the ET could be validated. Objectives. To record changes in ME pressure over a period of time in normal human ears, while the ET is kept closed. Subjects and methods. On-line tympanometry was carried out in three subjects, who refrained from swallowing for 20-120 min. Results. During the time when the ET was kept closed by refraining from swallowing, tympanometric monotonous pressure decrease was recorded. Once the tested subject could not refrain from swallowing any longer and swallowed again, ME pressure equalized immediately.
引用
收藏
页码:1182 / 1186
页数:5
相关论文
共 15 条
[1]   Tympanometry versus direct middle ear pressure measurement in an artificial model:: Is tympanometry an accurate method to measure middle ear pressure? [J].
Cinamon, U ;
Sadé, J .
OTOLOGY & NEUROTOLOGY, 2003, 24 (06) :850-853
[2]   NORMAL GAS-EXCHANGE IN HUMAN MIDDLE-EAR [J].
ELNER, A .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1976, 85 (02) :161-164
[3]  
FELDING JU, 1987, SCAND J CLIN LAB I S, V177, P493
[4]  
Gaihede M, 2000, Auris Nasus Larynx, V27, P231, DOI 10.1016/S0385-8146(99)00055-3
[5]   HUMAN MIDDLE-EAR GAS-COMPOSITION STUDIED BY MASS-SPECTROMETRY [J].
HERGILS, L ;
MAGNUSON, B .
ACTA OTO-LARYNGOLOGICA, 1990, 110 (1-2) :92-99
[6]   Experimental model for investigating trans-mucosal gas exchanges in the middle ear of the rat [J].
Kania, R ;
Portier, F ;
Lecain, E ;
Marcusohn, Y ;
Ar, A ;
Herman, P ;
Huy, PTB .
ACTA OTO-LARYNGOLOGICA, 2004, 124 (04) :408-410
[7]   Role of nitrogen in transmucosal gas exchange rate in the rat middle ear [J].
Kania, Romain E. ;
Herman, Philippe ;
Huy, Patrice Tran Ba ;
Ar, Amos .
JOURNAL OF APPLIED PHYSIOLOGY, 2006, 101 (05) :1281-1287
[8]   RELATIONSHIP BETWEEN THE GAS-COMPOSITION OF THE MIDDLE-EAR AND THE VENOUS-BLOOD AT STEADY-STATE [J].
LUNTZ, M ;
LEVI, D ;
SADE, J ;
HERMAN, M .
LARYNGOSCOPE, 1995, 105 (05) :510-512
[9]   Rate of gas exchange in the middle ear of guinea pigs [J].
Mover-Lev, H ;
Sadé, J ;
Ar, A .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1998, 107 (03) :194-198
[10]   TYMPANOMETRICAL STUDIES IN MIDDLE-EAR MODELS [J].
PAU, HW ;
KOCH, U .
ARCHIV FUR OHREN-NASEN-UND KEHLKOPFHEILKUNDE-ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 1978, 221 (04) :261-267