Neutrophils and COVID-19: The road so far

被引：117

作者：

Agra Cavalcante-Silva, Luiz Henrique ^{[1
]}

Madruga Carvalho, Deyse Cristina ^{[1
]}

Lima, Essia de Almeida ^{[1
]}

Galvao, Jose G. F. M. ^{[1
]}

de Franca da Silva, Juliane S. ^{[1
]}

de Sales-Neto, Jose Marreiro ^{[1
]}

Rodrigues-Mascarenhas, Sandra ^{[1
]}

机构：

[1] Univ Fed Paraiba UFPB, Lab Imunobiotecnol, Ctr Biotecnol, Joao Pessoa, Paraiba, Brazil

来源：

INTERNATIONAL IMMUNOPHARMACOLOGY | 2021年 / 90卷

关键词：

Inflammation; Chemokines; NETs; SARS-CoV2; EXTRACELLULAR TRAPS; SARS-CORONAVIRUS; LYMPHOCYTE RATIO; INFECTIONS; AUTOIMMUNE; PNEUMONIA; ELASTASE; IMMUNITY; NETOSIS;

D O I：

10.1016/j.intimp.2020.107233

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The SARS-Cov2 infection triggers a multisystem inflammatory disorder, knowing as COVID-19, a pandemic disease. This disease is characterized by acute respiratory distress syndrome, cytokine-driven hyper inflammation, and leukocytes count changes. The innate immune response has been linked to COVID-19 immunopathogenesis (e.g., dysfunctional IFN response and myeloid inflammation). In this regard, neutrophils have been highlighted as essential effector cells in the development of COVID-19. This review summarized the significant finds about neutrophils and its effector mechanisms (e.g., neutrophils enzymes and cytokines, neutrophil extracellular traps) in COVID-19 so far.

引用

页数：7

共 50 条

[41] COVID-19 Disease and Ophthalmology: An Update [J].

Amesty, Maria A. ;

Alio del Barrio, Jorge L. ;

Alio, Jorge L. .

OPHTHALMOLOGY AND THERAPY, 2020, 9 (3) :1-12

[42] The role of extracellular histones in COVID-19 [J].

de Vries, Femke ;

Huckriede, Joram ;

Wichapong, Kanin ;

Reutelingsperger, Chris ;

Nicolaes, Gerry A. F. .

JOURNAL OF INTERNAL MEDICINE, 2023, 293 (03) :275-292

[43] Heterogeneous neutrophils in lung transplantation and proteolytic CXCL8 activation in COVID-19, influenza and lung transplant patient lungs [J].

Cambier, Seppe ;

Beretta, Fabio ;

Nooyens, Amber ;

Metzemaekers, Mieke ;

Portner, Noemie ;

Kaes, Janne ;

de Carvalho, Ana Carolina ;

Cortesi, Emanuela E. ;

Beeckmans, Hanne ;

Hooft, Charlotte ;

Gouwy, Mieke ;

Struyf, Sofie ;

Marques, Rafael E. ;

Ceulemans, Laurens J. ;

Wauters, Joost ;

Vanaudenaerde, Bart M. ;

Vos, Robin ;

Proost, Paul .

CELLULAR AND MOLECULAR LIFE SCIENCES, 2024, 81 (01)

[44] COVID-19 and Neutrophils: The Relationship between Hyperinflammation and Neutrophil Extracellular Traps [J].

Borges, Leandro ;

Pithon-Curi, Tania Cristina ;

Curi, Rui ;

Hatanaka, Elaine .

MEDIATORS OF INFLAMMATION, 2020, 2020

[45] COVID-19 and Diabetes: will Novel Drugs for Diabetes Help in COVID-19? [J].

Al-kuraishy, Hayder Mutter ;

Al-Gareeb, Ali Ismail ;

Mostafa-Hedeab, Gomaa ;

Dubey, Rupal ;

Prabhakar, Pranav Kumar ;

Batiha, Gaber El-Saber .

CURRENT MOLECULAR PHARMACOLOGY, 2023, 16 (04) :494-506

[46] Covid-19: a comprehensive review of a formidable foe and the road ahead [J].

Hussain, Md. Arafat ;

Yadav, Suniti ;

Hadda, Vijay ;

Suri, Tejas M. ;

Tiwari, Pawan ;

Mittal, Saurabh ;

Madan, Karan ;

Mohan, Anant .

EXPERT REVIEW OF RESPIRATORY MEDICINE, 2020, 14 (09) :869-879

[47] Telomeres and COVID-19 [J].

Aviv, Abraham .

FASEB JOURNAL, 2020, 34 (06) :7247-7252

[48] Diabetes and COVID-19 [J].

Bouhanick, Beatrice ;

Cracowski, Jean-Luc ;

Faillie, Jean-Luc .

THERAPIE, 2020, 75 (04) :327-333

[49] COVID-19 and the Heart [J].

Akhmerov, Akbarshakh ;

Marban, Eduardo .

CIRCULATION RESEARCH, 2020, 126 (10) :1443-1455

[50] An overview of COVID-19 [J].

Shi, Yu ;

Wang, Gang ;

Cai, Xiao-peng ;

Deng, Jing-wen ;

Zheng, Lin ;

Zhu, Hai-hong ;

Zheng, Min ;

Yang, Bo ;

Chen, Zhi .

JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B, 2020, 21 (05) :343-360

← 1 2 3 4 5 →