Antioxidant effect of polyphenolic glabridin on LDL oxidation

被引：33
|
作者：
Carmeli, E. [1 ]
Fogelman, Y. [1 ]
机构：
[1] Tel Aviv Univ, Dept Phys Therapy, Sackler Fac Med, Ramat Aviv, Israel
来源：
TOXICOLOGY AND INDUSTRIAL HEALTH | 2009年 / 25卷 / 4-5期
关键词：
antiatherosclerotic affects; cardiovascular diseases; glabridin; LDL oxidation; licorice plant; Sienna conference; LOW-DENSITY-LIPOPROTEIN; LICORICE EXTRACT; FREE-RADICALS; ATHEROSCLEROSIS; INCREASES; DISEASE; STRESS; MICE;
D O I：
10.1177/0748233709103034
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
This study was conducted to determine the effect of a natural polyphenolic isoflavone antioxidant (Glabridin) on low-density lipoprotein (LDL) oxidation. Determination of the extent of LDL oxidation was done by measuring the formation of Thiobarbituric acid reactive substances (TBARS). After oral administration of licorice-root ethanol extract to healthy subjects for 6 months, the subjects' oxidative stress level as well as plasma LDL oxidation reduced by 20%. We concluded that dietary consumption of glabridin protects LDL from oxidation. Toxicology and Industrial Health 2009; 25: 321-324.
引用
收藏
页码：321 / 324
页数：4
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