Supported lipid bilayer self-spreading on a nanostructured silicon surface

被引:46
|
作者
Furukawa, Kazuaki [1 ]
Sumitomo, Koji [1 ]
Nakashima, Hiroshi [1 ]
Kashimura, Yoshiaki [1 ]
Torimitsu, Keiichi [1 ]
机构
[1] NTT Corp, NTT Basic Res Labs, Atsugi, Kanagawa 2430198, Japan
关键词
D O I
10.1021/la062911d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report on the self-spreading behavior of a supported lipid bilayer (SLB) on a silicon surface with various 100 nm nanostructures. SLBs have been successfully grown from a small spot of a lipid molecule source both on a flat surface and uneven surfaces with 100 nm up-and-down nanostructures. After an hour, the self-spreading SLB forms a large circle or an ellipse depending on the nanostructure pattern. The results are explained by a model that shows that a single-layer SLB grows along the nanostructured surfaces. The model is further supported by a quantitative analyses of our data. We also discuss the stability of the SLB on nanostructured surfaces in terms of the balance between its bending and adhesion energies.
引用
收藏
页码:367 / 371
页数:5
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