Microstructure and properties of a calcium phosphate cement tissue engineering scaffold modified with collagen and chitosan

被引：3

作者：

Wang, Xiupeng ^{[1
]}

Ye, Jiandong ^{[1
]}

Chen, Ling ^{[2
]}

Wang, Yingjun ^{[1
]}

机构：

[1] South China Univ Technol, Minist Educ, Key Lab Specially Funct Mat, Guangzhou 510641, Peoples R China

[2] South China Univ Technol, Inst Light Ind & Chem Engn, Guangzhou 510641, Peoples R China

来源：

BIOCERAMICS, VOL 19, PTS 1 AND 2 | 2007年 / 330-332卷

基金：

中国国家自然科学基金;

关键词：

calcium phosphate cement; tissue engineering scaffold; collagen; chitosan;

D O I：

10.4028/www.scientific.net/KEM.330-332.983

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

In this Study, an ACP-DCPD based Calcium phosphate cement (CPC) scaffold with a porosity of 88% was prepared by using Na3PO4 as a poregen and then modified by collagen and chitosan. The results showed that collagen and chitosan obviously increased the compressive strength. Cell Culture showed that the cell can migrate, attach, proliferate and differentiate on the surface of the materials and the pores walls. This CPC scaffold modified with collagen or chitosan was a promising material to be used in bone tissue engineering.

引用

页码：983 / +

页数：2

共 9 条

[1] Mechanical and in vivo performance of hydroxyapatite implants with controlled architectures [J].

Chu, TMG ;

Orton, DG ;

Hollister, SJ ;

Feinberg, SE ;

Halloran, JW .

BIOMATERIALS, 2002, 23 (05) :1283-1293

[2] A new method to produce macropores in calcium phosphate cements [J].

del Real, RP ;

Wolke, JGC ;

Vallet-Regí, M ;

Jansen, JA .

BIOMATERIALS, 2002, 23 (17) :3673-3680

[3] Role of interconnections in porous bioceramics on bone recolonization in vitro and in vivo [J].

Lu, JX ;

Flautre, B ;

Anselme, K ;

Hardouin, P ;

Gallur, A ;

Descamps, M ;

Thierry, B .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 1999, 10 (02) :111-120

[4] Influence of surfactant molecules as air-entraining agent for bone cement macroporosity [J].

Sarda, S ;

Nilsson, M ;

Balcells, M ;

Fernández, E .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2003, 65A (02) :215-221

[5]

TAKAGI S, 1995, J DENT RES, V74, P559

[6]

Takagi T, 2000, INT J APPL ELECTROM, V12, P1

[7]

WANG XP, IN PRESS J BIOMED MA

[8] Gelatin manipulation of latent macropores formation in brushite cement [J].

Yin, YJ ;

Ye, F ;

Cai, S ;

Yao, KD ;

Cui, JF ;

Song, XF .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2003, 14 (03) :255-261

[9]

Yoshikawa T, 1996, BIO-MED MATER ENG, V6, P345

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