Protein Identification as an Information Retrieval Problem

被引:0
|
作者
Yang, Yiming [1 ]
Ganapathy, Subramaniam [1 ]
Harpale, Abhay [1 ]
机构
[1] Carnegie Mellon Univ, Pittsburgh, PA 15213 USA
关键词
Interdisciplinary Investigation; Protein Identification; Tandem Mass Spectra;
D O I
10.1145/1571941.1572111
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
We present the first interdisciplinary work on transforming a popular problem in proteomics, i.e. protein identification from tandem mass spectra, to an Information Retrieval (IR) problem. We present an empirical comparison of popular IR approaches, such as those available from Indri and Lemur toolkits on benchmark datasets, to representative popular baselines in the proteomics literature. Our experiments demonstrate statistically significant evidence that popular IR approaches outperform representative baseline approaches in proteomics.
引用
收藏
页码:752 / 753
页数:2
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