Controlled overproduction of proteins by lactic acid bacteria

被引：167

作者：

Kuipers, OP ^{[1
]}

deRuyter, PGGA ^{[1
]}

Kleerebezem, M ^{[1
]}

deVos, WM ^{[1
]}

机构：

[1] WAGENINGEN UNIV AGR, DEPT MICROBIOL, NL-6703 CT WAGENINGEN, NETHERLANDS

来源：

TRENDS IN BIOTECHNOLOGY | 1997年 / 15卷 / 04期

关键词：

D O I：

10.1016/S0167-7799(97)01029-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Lactic acid bacteria are widely used in industrial food fermentations, contributing to flavour, texture and preservation of the fermented products. Here we describe recent advances in the development of controlled gene expression systems, which allow the regulated overproduction of any desirable protein by lactic acid bacteria. Some systems benefit from the fact that the expression vectors, marker genes and inducing factors can be used directly in food applications since they are all derived from food-grade lactic acid bacteria. These systems have also been employed for the development of autolytic bacteria, suitable for various industrial applications.

引用

页码：135 / 140

页数：6

共 33 条

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