机构:
Univ New S Wales, Prince Wales Med Res Inst, Randwick, NSW 2031, AustraliaUniv New S Wales, Prince Wales Med Res Inst, Randwick, NSW 2031, Australia
Cheng, Shaokoon
[1
]
Bilston, Lynne E.
论文数: 0引用数: 0
h-index: 0
机构:
Univ New S Wales, Prince Wales Med Res Inst, Randwick, NSW 2031, AustraliaUniv New S Wales, Prince Wales Med Res Inst, Randwick, NSW 2031, Australia
Bilston, Lynne E.
[1
]
机构:
[1] Univ New S Wales, Prince Wales Med Res Inst, Randwick, NSW 2031, Australia
brain tissues;
white matter;
unconfined compression;
poroviscoelastic;
stress relaxation;
D O I:
10.1016/j.jbiomech.2005.11.004
中图分类号:
Q6 [生物物理学];
学科分类号:
071011 ;
摘要:
The porous properties of brain tissue are important for understanding normal and abnormal cerebrospinal fluid flow in the brain. In this study, a poroviscoelastic model was fitted to the stress relaxation response of white matter in unconfined compression performed under a range of low strain rates. A set of experiments was also performed on the tissue samples using a no-slip boundary condition. Results from these experiments demonstrated that the rheological response of the white matter is primarily governed by the intrinsic viscoelastic properties of the solid phase. The permeability of white matter was found to be of the order of 10(-12) m(4)/Ns. (c) 2005 Elsevier Ltd. All rights reserved.