IPRATROPIUM BROMIDE COMBINED WITH BUDESONIDE CAN AMELIORATE THE PULMONARY FUNCTION AND INFLAMMATION OF PATIENTS WITH ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

被引：0
作者：
Ding, YaTing [1 ]
Wu, Xiaohui [2 ]
机构：
[1] Nantong Univ, Dept Pharm, Affiliated Hosp, Nantong 226001, Jiangsu, Peoples R China
[2] Nantong Univ, Dept Cardiol, Affiliated Hosp, Nantong 226001, Jiangsu, Peoples R China
来源：
ACTA MEDICA MEDITERRANEA | 2021年 / 37卷 / 01期
关键词：
Ipratropium bromide; budesonide; acute exacerbation of COPD; pulmonary function; inflammation; SMOKERS; SCALE;
D O I：
10.19193/0393-6384_2021_1_111
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective: To explore the effect of budesonide combined with ipratropium bromide on patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods: A total of 130 patients with acute exacerbation of COPD admitted to our hospital from November 2017 to July 2019 were enrolled and given basic treatment. The patients were randomly divided into Group A (n=68) and Group B (n=62). Patients in Group A were treated with ipratropium bromide solution and patients in Group B were treated with ipratropium bromide solution combined with budesonide inhalation suspension. The two groups were compared in the levels of inflammatory factors, pulmonary function, and adverse reactions. Results: After treatment, the levels of inflammatory factors, adverse reactions, and pulmonary function of Group B were all better than those of Group A (all P<0.05). Conclusion: Budesonide combined with ipratropium bromide is effective in the treatment of patients with acute exacerbation of COPD.
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收藏
页码：723 / 728
页数：6
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