Altered Motor-Striatal Plasticity and Cortical Functioning in Patients with Schizophrenia

被引：18
|
作者：
Zhou, Dongsheng [1 ]
Pang, Feng [2 ]
Liu, Shiyan [1 ]
Shen, Ying [3 ]
Liu, Lingjiang [1 ]
Fang, Zezhong [1 ]
Wang, Chuang [4 ]
Hu, Zhenyu [1 ]
Yuan, Ti-Fei [2 ]
机构：
[1] Ningbo Kangning Hosp, Ningbo Key Lab Behav Neurosci, Ningbo 315201, Zhejiang, Peoples R China
[2] Nanjing Normal Univ, Sch Psychol, Nanjing 210097, Jiangsu, Peoples R China
[3] Nanjing Med Univ, Rehabil Med Ctr, Affiliated Hosp 1, Nanjing 210029, Jiangsu, Peoples R China
[4] Ningbo Univ, Ningbo Key Lab Behav Neurosci, Sch Med, Ningbo 315211, Zhejiang, Peoples R China
来源：
NEUROSCIENCE BULLETIN | 2017年 / 33卷 / 03期
基金：
中国国家自然科学基金;
关键词：
Schizophrenia; Cortical plasticity; Motor learning; human; TRANSCRANIAL MAGNETIC STIMULATION; LONG-TERM POTENTIATION; CORTEX; NEUROPLASTICITY;
D O I：
10.1007/s12264-016-0079-9
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Patients with schizophrenia undergo changes in brain plasticity. In the present study, we characterized motor cortical-striatal plasticity in such patients. Compared with the potentiation following high-frequency repetitive transcranial magnetic stimulation in the control group, the patients demonstrated impaired plasticity of corticostriatal motor-evoked potentials recorded from hand muscles. Notably, the loss of cortical plasticity was correlated with impaired motor learning in a rotary pursuit task. Moreover, the loss of plasticity was correlated with the symptoms of schizophrenia. The results suggest that the progression of schizophrenia is accompanied by altered cortical plasticity and functioning.
引用
收藏
页码：307 / 311
页数：5
相关论文
共 50 条
  • [21] Transcranial magnetic stimulation and the motor learning-associated cortical plasticity
    Milos Ljubisavljevic
    Experimental Brain Research, 2006, 173 : 215 - 222
  • [22] Exploring motor cortical plasticity using transcranial magnetic stimulation in humans
    Ilic, TV
    Ziemann, U
    BIOPHYSICS FROM MOLECULES TO BRAIN: IN MEMORY OF RADOSLAV K. ANDJUS, 2005, 1048 : 175 - 184
  • [23] Transcranial magnetic stimulation and the motor learning-associated cortical plasticity
    Ljubisavljevic, Milos
    EXPERIMENTAL BRAIN RESEARCH, 2006, 173 (02) : 215 - 222
  • [24] Absence of postexercise and delayed facilitation of motor cortex excitability in restless legs syndrome: Evidence of altered cortical plasticity?
    Scalise, Anna
    Pittaro-Cadore, Italo
    Golob, Edward J.
    Gigli, Gian Luigi
    SLEEP, 2006, 29 (06) : 770 - 775
  • [25] Impaired Potentiation of Theta Oscillations During a Visual Cortical Plasticity Task in Patients With Schizophrenia
    Hamilton, Holly
    Roach, Brian
    Cavus, Idil
    Reinhart, Robert
    Teyler, Timothy
    Clapp, Wesley
    Ford, Judith
    Mathalon, Daniel
    NEUROPSYCHOPHARMACOLOGY, 2019, 44 (SUPPL 1) : 346 - 346
  • [26] Cortical motor neurophysiology of patients with schizophrenia: A study using transcranial magnetic stimulation
    Soubasi, Evanthia
    Chroni, Elisabeth
    Gourzis, Philippos
    Zisis, Athanasios
    Beratis, Stavroula
    Papathanasopoulos, Panayiotis
    PSYCHIATRY RESEARCH, 2010, 176 (2-3) : 132 - 136
  • [27] Motor Cortical Network Plasticity in Patients With Recurrent Brain Tumors
    Bulubas, Lucia
    Sardesh, Nina
    Traut, Tavish
    Findlay, Anne
    Mizuiri, Danielle
    Honma, Susanne M.
    Krieg, Sandro M.
    Berger, Mitchel S.
    Nagarajan, Srikantan S.
    Tarapore, Phiroz E.
    FRONTIERS IN HUMAN NEUROSCIENCE, 2020, 14
  • [28] BDNF-Val66Met-Polymorphism Impact on Cortical Plasticity in Schizophrenia Patients: A Proof-of-Concept Study
    Strube, Wolfgang
    Nitsche, Michael A.
    Wobrock, Thomas
    Bunse, Tilmann
    Rein, Bettina
    Herrmann, Maximiliane
    Schmitt, Andrea
    Nieratschker, Vanessa
    Witt, Stephanie H.
    Rietschel, Marcella
    Falkai, Peter
    Hasan, Alkomiet
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2015, 18 (04) : 1 - 11
  • [29] Motor cortical excitability in schizophrenia
    Pascual-Leone, A
    Manoach, DS
    Birnbaum, R
    Goff, DC
    BIOLOGICAL PSYCHIATRY, 2002, 52 (01) : 24 - 31
  • [30] Selective modulation of motor cortical plasticity during voluntary contraction of the antagonist muscle
    Fang, Jhih-Hong
    Huang, Ying-Zu
    Hwang, Ing-Shiou
    Chen, Jia-Jin J.
    EUROPEAN JOURNAL OF NEUROSCIENCE, 2014, 39 (12) : 2083 - 2088
12345