The Arabidopsis cytosolic ribosomal proteome: from form to function

被引:66
作者
Carroll, Adam J. [1 ]
机构
[1] Australian Natl Univ, Australian Res Council, Ctr Excellence Plant Energy Biol, Canberra, ACT 0200, Australia
关键词
Arabidopsis; sub-cellular proteomics; proteomics; ribosomes; cytosolic ribosomes; plants; translation; 80S ribosomes; MASS-SPECTROMETRIC ANALYSIS; SEMI-DOMINANT MUTATION; GENOME-WIDE ANALYSIS; MITOCHONDRIAL RIBOSOMES; AMINO-ACIDS; CHLAMYDOMONAS-REINHARDTII; TRANSLATION REINITIATION; MEDIATED INCORPORATION; MS/MS ANALYSIS; S6; KINASE;
D O I
10.3389/fpls.2013.00032
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The cytosolic ribosomal proteome of Arabidopsis thaliana has been studied intensively by a range of proteomics approaches and is now one of the most well characterized eukaryotic ribosomal proteomes. Plant cytosolic ribosomes are distinguished from other eukaryotic ribosomes by unique proteins, unique post-translational modifications and an abundance of ribosomal proteins for which multiple divergent paralogs are expressed and incorporated. Study of the A. thaliana ribosome has now progressed well beyond a simple cataloging of protein parts and is focused strongly on elucidating the functions of specific ribosomal proteins, their paralogous isoforms and covalent modifications. This review summarises current knowledge concerning the Arabidopsis cytosolic ribosomal proteome and highlights potentially fruitful areas of future research in this fast moving and important area.
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页数:14
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