The role of innate lymphoid cells 2 in the allergic inflammation

被引：0

作者：

Gawrysiak, Mateusz ^{[1
]}

Szewczyk, Robert ^{[1
]}

Kowalski, Marek L. ^{[1
]}

Chalubinski, Maciej ^{[1
]}

机构：

[1] Uniwersytet Med Lodzi, Klin Immunol & Alergii, Ul Pomorska 251, PL-92213 Lodz, Poland

来源：

ALERGIA ASTMA IMMUNOLOGIA | 2020年 / 25卷 / 02期

关键词：

ILC2; allergic inflammation; allergy; T2-type immune response; TYPE-2; IMMUNITY; AIRWAY; ASTHMA;

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

ILC2s are a very important element of the innate immunity. Physiologically, the take part in the defense of the host against helmint infections. In pathological conditions, they become a link in the series of immune events of allergic inflammatory response. ILC2s activated by tissue-derived alarmins, such as IL-33, IL-25 and TSLP, release IL-4 and IL-5 affecting immune effectory cells, thus enhancing T2-dependent immune responses.

引用

页码：64 / 69

页数：6

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