Measuring nanoparticle flow with the image structure function

被引:11
作者
Dienerowitz, Maria [1 ]
Lee, Michael [1 ]
Gibson, Graham [1 ]
Padgett, Miles [1 ]
机构
[1] Univ Glasgow, Sch Phys & Astron, SUPA, Glasgow G12 8QQ, Lanark, Scotland
关键词
MICROFLUIDICS;
D O I
10.1039/c3lc00028a
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We present a technique to measure the velocity and flow profiles of a nanofluid in a microfluidic channel. Importantly, we extract the flow velocity from a series of standard brightfield images without employing particle tracking or laser-enhanced methods. Our analysis retrieves the flow information from the image structure function of sub-diffraction limited nanoparticles in suspension. We are able to spatially resolve the flow velocity and map out the parabolic flow profile across the width of a microfluidic channel.
引用
收藏
页码:2359 / 2363
页数:5
相关论文
共 21 条
[1]   Magnetic nanoparticles for drug delivery [J].
Arruebo, Manuel ;
Fernandez-Pacheco, Rodrigo ;
Ibarra, M. Ricardo ;
Santamaria, Jesus .
NANO TODAY, 2007, 2 (03) :22-32
[2]  
Berne BJ, 2000, DYNAMIC LIGHT SCATTE
[3]  
Berthier J., 2009, MICROFLUIDICS BIOTEC, P38
[4]   Differential dynamic microscopy: Probing wave vector dependent dynamics with a microscope [J].
Cerbino, Roberto ;
Trappe, Veronique .
PHYSICAL REVIEW LETTERS, 2008, 100 (18)
[5]   Multipoint holographic optical velocimetry in microfluidic systems [J].
Di Leonardo, R ;
Leach, J ;
Mushfique, H ;
Cooper, JM ;
Ruocco, G ;
Padgett, MJ .
PHYSICAL REVIEW LETTERS, 2006, 96 (13)
[6]   Expanding the toolbox for nanoparticle trapping and spectroscopy with holographic optical tweezers [J].
Dienerowitz, M. ;
Gibson, G. ;
Dienerowitz, F. ;
Padgett, M. .
JOURNAL OF OPTICS, 2012, 14 (04)
[7]   Kinetics of colloidal fractal aggregation by differential dynamic microscopy [J].
Ferri, F. ;
D'Angelo, A. ;
Lee, M. ;
Lotti, A. ;
Pigazzini, M. C. ;
Singh, K. ;
Cerbino, R. .
EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS, 2011, 199 (01) :139-148
[8]   Scattering information obtained by optical microscopy: Differential dynamic microscopy and beyond [J].
Giavazzi, Fabio ;
Brogioli, Doriano ;
Trappe, Veronique ;
Bellini, Tommaso ;
Cerbino, Roberto .
PHYSICAL REVIEW E, 2009, 80 (03)
[9]   Microfluidics: Honey, I shrunk the lab [J].
Knight, J .
NATURE, 2002, 418 (6897) :474-475
[10]   Single-molecule DNA amplification and analysis in an integrated microfluidic device [J].
Lagally, ET ;
Medintz, I ;
Mathies, RA .
ANALYTICAL CHEMISTRY, 2001, 73 (03) :565-570