Toluene Abuse and White Matter A Model of Toxic Leukoencephalopathy

被引：24
|
作者：
Filley, Christopher M. [1 ]
机构：
[1] Univ Colorado, Sch Med, Behav Neurol Sect, Aurora, CO 80045 USA
来源：
PSYCHIATRIC CLINICS OF NORTH AMERICA | 2013年 / 36卷 / 02期
关键词：
Toluene; White matter; Dementia; Toxic; Leukoencephalopathy; Inhalants; BRAIN; INHALANT; ABNORMALITIES; ADOLESCENTS; PATHWAYS; EXPOSURE; SOLVENTS;
D O I：
10.1016/j.psc.2013.02.008
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
The brain is the primary target of toluene (methylbenzene), the major solvent in spray paint and a constituent of many other easily obtained commercial and industrial products. The effects of acute intoxication can be dramatic and the lasting adverse effects of inhalants may be highly injurious. Mental status alterations range from acute confusional state to coma. Toluene abuse effects on white matter are demonstrable neuroradiologically and neuropathologically, and have important neurobehavioral consequences.
引用
收藏
页码：293 / +
页数：11
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