Simple tandem repeat polymorphisms in the neuronal nitric oxide synthase gene in different ethnic populations

被引：29

作者：

Grasemann, H

Drazen, JM

Deykin, A

Israel, E

De Sanctis, GT

Pillari, A

Yandava, CN

机构：

[1] Brigham & Womens Hosp, Div Pulm & Crit Care Med, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA 02115 USA

来源：

HUMAN HEREDITY | 1999年 / 49卷 / 03期

关键词：

neuronal nitric oxide synthase gene; DNA polymorphism; CA repeat; AAT repeat; microsatellite; population study;

D O I：

10.1159/000022861

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Allelic frequencies of a CA dinucleotide repeat in exon 29 and an intronic AAT trinucleotide repeat in the neuronal nitric oxide synthase (NOS1) gene were determined by simple sequence length polymorphism (SSLP) in 305 American-Caucasian and 105 African-American healthy subjects, There were highly significant differences in allele frequencies between the two ethnically diverse study populations.

引用

页码：139 / 141

页数：3

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