Early colorectal cancer: diagnosis, treatment and survivorship care

被引:158
作者
Buccafusca, Gabriella [1 ]
Proserpio, Ilaria [2 ]
Tralongo, Antonino Carmelo [2 ]
Giuliano, Sebastiano Rametta [1 ]
Tralongo, Paolo [1 ]
机构
[1] Osped Umberto I, UOC Oncol Med, Via Giuseppe Testaferrata 1, I-96100 Siracusa, Italy
[2] Osped Circalo & Fdn Macchi, ASST Settelaghi, UOC Oncol Med, Via Francesco Guicciardini 9, I-21100 Varese, Italy
关键词
Cancer survivors; Cured; late/long term side effects; Life-style; III COLON-CANCER; ADVANCED RECTAL-CANCER; RANDOMIZED PHASE-III; INDUCED PERIPHERAL NEUROPATHY; QUALITY-OF-LIFE; COMPLETE MESOCOLIC EXCISION; TOTAL MESORECTAL EXCISION; SHORT-COURSE RADIOTHERAPY; OXALIPLATIN-BASED CHEMOTHERAPY; CLINICAL-PRACTICE GUIDELINES;
D O I
10.1016/j.critrevonc.2019.01.023
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
CRC is the third most commonly diagnosed malignancy and the fourth leading cause of cancer-related death in the world. With advances in treatment, colorectal cancer is being transformed from a deadly disease to an illness that is increasingly curable. With this transformation has come increased interest in the unique problems, risks, needs, and concerns of survivors who have completed treatment and are cancer-free. They often suffer late/long-term side effects of therapies that may compromise their QoL such as fatigue, sleep difficulty, fear of recurrence, anxiety, depression, negative body image, sensory neuropathy, gastrointestinal problems, urinary incontinence, and sexual dysfunction. In this review, we discuss what is known about early colorectal diagnosis, staging, treatments and their long-term effects on quality of life and survivorship care.
引用
收藏
页码:20 / 30
页数:11
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