An energy fluence-convolution model for amorphous silicon EPID dose prediction

被引:26
作者
Greer, Peter B. [1 ,2 ]
Cadman, Patrick [3 ]
Lee, Christopher [2 ,4 ]
Bzdusek, Karl [5 ]
机构
[1] Calvary Mat Newcastle Hosp, Dept Radiat Oncol, Hunter Reg Mail Ctr, Newcastle, NSW 2310, Australia
[2] Univ Newcastle, Sch Phys & Math Sci, Callaghan, NSW 2308, Australia
[3] Saskatchewan Canc Agcy, Dept Med Phys, Saskatoon, SK S7N 4H4, Canada
[4] Cent Coast Radiat Oncol Ctr, Gosford, NSW 2250, Australia
[5] Phillips Radiat Oncol Syst, Fitchburg, WI 53711 USA
关键词
dosimetry; radiation therapy; silicon; PORTAL IMAGING DEVICE; OPTIMAL BACKSCATTER; IMRT VERIFICATION; RECONSTRUCTION; IMAGES; CALIBRATION; DOSIMETRY; FIELDS;
D O I
10.1118/1.3058481
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
In this work, an amorphous silicon electronic portal imaging device (a-Si EPID) dose prediction model based on the energy fluence model of the Pinnacle treatment planning system Version 7 (Philips Medical Systems, Madison, WI) is developed. An energy fluence matrix at very high resolution (< 1 mm) is used to incorporate multileaf collimator (MLC) leaf effects in the predicted EPID images. The primary dose deposited in the EPID is calculated from the energy fluence using experimentally derived radially dependent EPID interaction coefficients. Separate coefficients are used for the open beam energy fluence component and the component of the energy fluence transmitted through closed MLC leaves to each EPID pixel. A spatially invariant EPID dose deposition kernel that describes both radiative dose deposition, central axis EPID backscatter, and optical glare is convolved with the primary dose. The kernel is further optimized to give accurate EPID penumbra prediction and EPID scatter factor with changing MLC field size. An EPID calibration method was developed to reduce the effect of nonuniform backscatter from the support arm (E-arm) in a calibrated EPID image. This method removes the backscatter component from the pixel sensitivity (flood field) correction matrix retaining only field-specific backscatter in the images. The model was compared to EPID images for jaw and MLC defined open fields and eight head and neck intensity modulated radiotherapy (IMRT) fields. For the head and neck IMRT fields with 2%, 2 mm criteria 97.6 +/- 0.6% (mean +/- 1 standard deviation) of points passed with a gamma index less than 1, and for 3%, 3 mm 99.4 +/- 0.4% of points were within the criteria. For these fields, the 2%, 2 mm pass score reduced to 96.0 +/- 1.5% when backscatter was present in the pixel sensitivity correction matrix. The model incorporates the effect of MLC leaf transmission, EPID response to open and MLC leakage dose components, and accurately predicts EPID images of IMRT fields. Removing the backscatter component of the pixel sensitivity matrix correction reduces the effect of nonuniform E-arm backscatter.
引用
收藏
页码:547 / 555
页数:9
相关论文
共 15 条
[1]   Three-dimensional portal image-based dose reconstruction in a virtual phantom for rapid evaluation of IMRT plans [J].
Ansbacher, W. .
MEDICAL PHYSICS, 2006, 33 (09) :3369-3382
[2]   Validation of physics improvements for IMRT with a commercial treatment-planning system [J].
Cadman, Patrick ;
McNutt, Todd ;
Bzdusek, Karl .
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 2005, 6 (02) :74-86
[3]   Correction of pixel sensitivity variation and off-axis response for amorphous silicon EPID dosimetry [J].
Greer, PB .
MEDICAL PHYSICS, 2005, 32 (12) :3558-3568
[4]   Experimental investigation of the response of an amorphous silicon EPID to intensity modulated radiotherapy beams [J].
Greer, Peter B. ;
Vial, Philip ;
Oliver, Lyn ;
Baldock, Clive .
MEDICAL PHYSICS, 2007, 34 (11) :4389-4398
[5]   Comprehensive Monte Carlo calculation of the point spread function for a commercial a-Si EPID [J].
Kirkby, C ;
Sloboda, R .
MEDICAL PHYSICS, 2005, 32 (04) :1115-1127
[6]   Investigation of the optimal backscatter for an aSi electronic portal imaging device [J].
Ko, L ;
Kim, JO ;
Siebers, JV .
PHYSICS IN MEDICINE AND BIOLOGY, 2004, 49 (09) :1723-1738
[7]   Using fluence separation to account for energy spectra dependence in computing dosimetric a-Si EPID images for IMRT fields [J].
Li, Weidong ;
Siebers, Jeffrey V. ;
Moore, Joseph A. .
MEDICAL PHYSICS, 2006, 33 (12) :4468-4480
[8]   Verification of the optimal backscatter for an aSi electronic portal imaging device [J].
Moore, JA ;
Siebers, JV .
PHYSICS IN MEDICINE AND BIOLOGY, 2005, 50 (10) :2341-2350
[9]   GLAaS: An absolute dose calibration algorithm for an amorphous silicon portal imager. Applications to IMRT verifications [J].
Nicolini, Giorgia ;
Fogliata, Antonella ;
Vanetti, Eugenio ;
Clivio, Alessandro ;
Cozzi, Luca .
MEDICAL PHYSICS, 2006, 33 (08) :2839-2851
[10]   Amorphous silicon EPID calibration for dosimetric applications: comparison of a method based on Monte Carlo prediction of response with existing techniques [J].
Parent, L. ;
Fielding, A. L. ;
Dance, D. R. ;
Seco, J. ;
Evans, P. M. .
PHYSICS IN MEDICINE AND BIOLOGY, 2007, 52 (12) :3351-3368