Screening of pharmacologic adulterant classes in herbal formulations using voltammetry of microparticles

被引：34

作者：

Domenech-Carbo, Antonio ^{[1
]}

Martini, Mariele ^{[2
]}

Machado de Carvalho, Leandro ^{[2
]}

Viana, Carine ^{[2
]}

Teresa Domenech-Carbo, Maria ^{[3
]}

Silva, Miguel ^{[3
]}

机构：

[1] Univ Valencia, Dept Quim Analit, E-46100 Burjassot, Valencia, Spain

[2] Univ Fed Santa Maria, BR-97105970 Santa Maria, RS, Brazil

[3] Univ Politecn Valencia, Dept Conservacio & Restauracio Bens Culturals, Inst Restauracio Patrimoni, Valencia 46022, Spain

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2013年 / 74卷

关键词：

Adulterants; Herbal formulations; Screening; Voltammetry of microparticles; AFM; PERFORMANCE LIQUID-CHROMATOGRAPHY; SQUARE-WAVE VOLTAMMETRY; MERCURY DROP ELECTRODE; WALL CARBON NANOTUBES; ORGANIC-DYES; CAPILLARY-ELECTROPHORESIS; ELECTROCHEMICAL ANALYSIS; PULSE POLAROGRAPHY; GRAPHITE ELECTRODE; BIOLOGICAL-FLUIDS;

D O I：

10.1016/j.jpba.2012.10.031

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A solid state electrochemical method for screening different families of adulterant chemicals illegally added to commercial phytotherapuetic formulations is described. The proposed method, based on the voltammetry of microparticles approach, permits a fast and sensitive way to distinguish between anorexics (amfepramone, fenproporex, sibutramine), benzozodiazepinic anxiolytics (clonazepam, flurazepam, alprazolam, midazolam, medazepam, chlordiazepoxide, diazepam), antidepressants (bupropione, fluoxetine, sertraline, paroxetine), diuretics (hydrochlorothiazide, furosemide, chlortalidone, amiloride, spironolactone), and hypoglycemics (glimepiride, chlorpropamide, glibenclamide) based on characteristic voltammetric signals recorded on solid micro- or nanosamples attached to graphite electrodes immersed into aqueous electrolytes. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：194 / 204

页数：11

共 56 条

[1] Determination of amfepramone hydrochloride, fenproporex, and diazepam in so-called "natural" capsules used in the treatment of obesity
Almeida, AE
Ribeiro, ML
Polese, L
[J]. JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2000, 23 (07) : 1109 - 1118
[2] Electrochemical quartz crystal microbalance studies of single-wall carbon nanotubes in aqueous and non-aqueous solutions
Barisci, JN
Wallace, GG
Baughman, RH
[J]. ELECTROCHIMICA ACTA, 2000, 46 (04) : 509 - 517
[3] Electrochemical studies of single-wall carbon nanotubes in aqueous solutions
Barisci, JN
Wallace, GG
Baughman, RH
[J]. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2000, 488 (02): : 92 - 98
[4] The electrochemical reduction of indigo dissolved in organic solvents and as a solid mechanically attached to a basalt plane pyrolytic graphite electrode immersed in aqueous electrolyte solution
Bond, AM
Marken, F
Hill, E
Compton, RG
Hugel, H
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1997, (09): : 1735 - 1742
[5] Electrochemical and X-ray diffraction study of the redox cycling of nanocrystals of 7,7,8,8-tetracyanoquinodimethane - Observation of a solid-solid phase transformation controlled by nucleation and growth
Bond, AM
Fletcher, S
Marken, F
Shaw, SJ
Symons, PG
[J]. JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS, 1996, 92 (20): : 3925 - 3933
[6] H-point standard addition method applied to voltammetry of microparticles.: Quantitation of dyes in pictorial samples
Bosch-Reig, F.
Domenech-Carbo, A.
Domenech-Carbo, M. T.
Gimeno-Adelantado, J. V.
[J]. ELECTROANALYSIS, 2007, 19 (15) : 1575 - 1584
[7] DETERMINATION OF 1,4-BENZODIAZEPINES IN BIOLOGICAL-FLUIDS BY DIFFERENTIAL PULSE POLAROGRAPHY
BROOKS, MA
SILVA, JAFD
[J]. TALANTA, 1975, 22 (10-1) : 849 - 860
[8] Analysis of coptisine, berberine and palmatine in adulterated Chinese medicine by capillary electrophoresis-electrospray ion trap mass spectrometry
Chen, YR
Wen, KC
Her, GR
[J]. JOURNAL OF CHROMATOGRAPHY A, 2000, 866 (02) : 273 - 280
[9] Adulteration of herbal antidiabetic products with undeclared pharmaceuticals: a case series in Hong Kong
Ching, Chor Kwan
Lam, Ying Hoo
Chan, Albert Y. W.
Mak, Tony W. L.
[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2012, 73 (05) : 795 - 800
[10] de Azeredo F.S., 2004, REV ELETRONICA FARMA, V1, P17

← 1 2 3 4 5 6 →