Inflammatory Response Inhibition and Improvement of COVID-19 Symptoms in COVID-19 Patients by Combination of Antiviral Regimen and Tanreqing Injection

被引：0

作者：

Gong, Xiangwen ^{[1
]}

Liu, Chunyun ^{[1
]}

Huang, Yumei ^{[1
]}

Jiang, Zewen ^{[2
]}

Luo, Yunfeng ^{[3
]}

Zhong, Jin ^{[2
]}

Xiao, Xinfa ^{[1
]}

Li, Zhiteng ^{[1
]}

Chen, Qian ^{[1
]}

Xie, Zongyan ^{[1
]}

Yi, Jisan ^{[4
]}

Liu, Hui ^{[1
]}

Gang, Fang ^{[5
]}

机构：

[1] Fifth Peoples Hosp Ganzhou, Ganzhou Inst Resp Dis, Dept Resp & Crit Care Med, Ganzhou 341000, Jiangxi, Peoples R China

[2] Xinfeng Cty Peoples Hosp, Dept Resp Dis, Xinfeng 341600, Jiangxi, Peoples R China

[3] Ganxian Dist Peoples Hosp Ganzhou City, Dept Infect Dis, Gan County 341100, Jiangxi, Peoples R China

[4] Yudu Cty Hosp, Dept Infect Dis, Ganzhou 342300, Jiangxi, Peoples R China

[5] Guangxi Univ Chinese Med, Guangxi Key Lab Appl Fundamental Res Zhuang Med, Nanning 530200, Guangxi, Peoples R China

来源：

LATIN AMERICAN JOURNAL OF PHARMACY | 2022年 / 41卷 / 02期

关键词：

clinical efficacy; COVID-19; inflammatory response; Tanreqing injection;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The present study explored the inflammatory response and clinical efficacy of Tanreqing injection in combination with antiviral therapy in patients with coronavirus disease (COVID-19). The results demonstrated that the levels of C-reactive protein (CRP) and interleukin-6 (IL-6) in the treatment group were significantly lower than those in the control group (p < 0.05). Clinical efficacy assessment revealed a significant improvement in the time necessary for image absorption improvement in the treatment group (p < 0.05), while the time taken for fever and muscle soreness symptoms to resolve significantly reduced (p < 0.05). Furthermore, the time taken to obtain a negative COVID-19 test result was significantly shortened (p < 0.05). Tanreqing injection combined with antiviral treatment improved clinical symptoms of COVID-19 faster than when the anti-viral treatments were used alone and this may be related to the reduction in inflammatory response.

引用

页码：413 / 419

页数：7

共 18 条

[1] Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected. Interim guidance [J].

不详 .

PEDIATRIA I MEDYCYNA RODZINNA-PAEDIATRICS AND FAMILY MEDICINE, 2020, 16 (01) :9-26

[2] Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study [J].

Chen, Nanshan ;

Zhou, Min ;

Dong, Xuan ;

Qu, Jieming ;

Gong, Fengyun ;

Han, Yang ;

Qiu, Yang ;

Wang, Jingli ;

Liu, Ying ;

Wei, Yuan ;

Xia, Jia'an ;

Yu, Ting ;

Zhang, Xinxin ;

Zhang, Li .

LANCET, 2020, 395 (10223) :507-513

[3] Progress and prospect on imaging diagnosis of COVID-19 [J].

Fan, Li ;

Li, Dong ;

Xue, Huadan ;

Zhang, Longjiang ;

Liu, Zaiyi ;

Zhang, Bing ;

Zhang, Lina ;

Yang, Wenjie ;

Xie, Baojun ;

Duan, Xiaoyi ;

Hu, Xiuhua ;

Cheng, Kailiang ;

Peng, Liqing ;

Yu, Nan ;

Song, Lan ;

Chen, Huai ;

Sui, Xin ;

Zheng, Nannan ;

Liu, Shiyuan ;

Jin, Zhengyu .

CHINESE JOURNAL OF ACADEMIC RADIOLOGY, 2020, 3 (01) :4-13

[4]

General Office of the National Health Commission, 2020, NOTICE PRINTING DIS

[5] Three Emerging Coronaviruses in Two Decades The Story of SARS, MERS, and Now COVID-19 [J].

Guarner, Jeannette .

AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2020, 153 (04) :420-421

[6] Application of metabolomics in viral pneumonia treatment with traditional Chinese medicine [J].

Lin, Lili ;

Yan, Hua ;

Chen, Jiabin ;

Xie, Huihui ;

Peng, Linxiu ;

Xie, Tong ;

Zhao, Xia ;

Wang, Shouchuan ;

Shan, Jinjun .

CHINESE MEDICINE, 2019, 14 (1)

[7] Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data [J].

Linton, Natalie M. ;

Kobayashi, Tetsuro ;

Yang, Yichi ;

Hayashi, Katsuma ;

Akhmetzhanov, Andrei R. ;

Jung, Sung-mok ;

Yuan, Baoyin ;

Kinoshita, Ryo ;

Nishiura, Hiroshi .

JOURNAL OF CLINICAL MEDICINE, 2020, 9 (02)

[8] Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients [J].

Liu, Jin ;

Li, Sumen ;

Liu, Jia ;

Liang, Boyun ;

Wang, Xiaobei ;

Wang, Hua ;

Li, Wei ;

Tong, Qiaoxia ;

Yi, Jianhua ;

Zhao, Lei ;

Xiong, Lijuan ;

Guo, Chunxia ;

Tian, Jin ;

Luo, Jinzhuo ;

Yao, Jinghong ;

Pang, Ran ;

Shen, Hui ;

Peng, Cheng ;

Liu, Ting ;

Zhang, Qian ;

Wu, Jun ;

Xu, Ling ;

Lu, Sihong ;

Wang, Baoju ;

Weng, Zhihong ;

Han, Chunrong ;

Zhu, Huabing ;

Zhou, Ruxia ;

Zhou, Helong ;

Chen, Xiliu ;

Ye, Pian ;

Zhu, Bin ;

Wang, Lu ;

Zhou, Wenqing ;

He, Shengsong ;

He, Yongwen ;

Jie, Shenghua ;

Wei, Ping ;

Zhang, Jianao ;

Lu, Yinping ;

Wang, Weixian ;

Zhang, Li ;

Li, Ling ;

Zhou, Fengqin ;

Wang, Jun ;

Dittmer, Ulf ;

Lu, Mengji ;

Hu, Yu ;

Yang, Dongliang ;

Zheng, Xin .

EBIOMEDICINE, 2020, 55

[9] A Minimax Optimal Ridge-Type Set Test for Global Hypothesis With Applications in Whole Genome Sequencing Association Studies [J].

Liu, Yaowu ;

Li, Zilin ;

Lin, Xihong .

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 2022, 117 (538) :897-908

[10]

Luo Yu, 2016, Zhongguo Zhong Yao Za Zhi, V41, P850, DOI 10.4268/cjcmm20160515

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