Parabens. From environmental studies to human health

被引:554
作者
Bledzka, Dorota [1 ]
Gromadzinska, Jolanta [1 ]
Wasowicz, Wojciech [1 ]
机构
[1] Nofer Inst Occupat Med, Dept Toxicol & Carcinogenesis, PL-91348 Lodz, Poland
关键词
Paraben; Preservative; Occurrence in the environment; Endocrine disruptor; Cancer; Oxidative stress; P-HYDROXYBENZOIC ACID; PERSONAL-CARE PRODUCTS; ENDOCRINE-DISRUPTING COMPOUNDS; TANDEM MASS-SPECTROMETRY; BENZOATE PRESERVATIVES PARABENS; PRESSURIZED LIQUID EXTRACTION; TROUT ONCORHYNCHUS-MYKISS; MALE REPRODUCTIVE-SYSTEM; BODY TOPICAL APPLICATION; BAR SORPTIVE EXTRACTION;
D O I
10.1016/j.envint.2014.02.007
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Parabens are a group of substances commonly employed as preservatives, mainly in personal care products, pharmaceuticals and food. Scientific reports concerning their endocrine disrupting potential and the possible link with breast cancer raised wide discussion about parabens' impact and safety. This paper provides holistic overview of paraben usage, occurrence in the environment, methods of their degradation and removal from aqueous solution, as well as hazards related to their endocrine disrupting potential and possible involvement in carcinogenesis. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:27 / 42
页数:16
相关论文
共 174 条
[1]  
Aguilar-Bernier M, 2012, ACTAS DERMO-SIFILOGR, V103, P223, DOI [10.1016/j.adengl.2011.07.008, 10.1016/j.ad.2011.07.010]
[2]   Occurrence and analysis of parabens in municipal sewage sludge from wastewater treatment plants in Madrid (Spain) [J].
Albero, Beatriz ;
Ana Perez, Rosa ;
Sanchez-Brunete, Consuelo ;
Luis Tadeo, Jose .
JOURNAL OF HAZARDOUS MATERIALS, 2012, 239 :48-55
[3]   Screening and testing for endocrine disruption in fish - Biomarkers as "signposts," not "traffic lights," in risk assessment [J].
Hutchinson, Thomas H. ;
Ankley, Gerald T. ;
Segner, Helmut ;
Tyler, Charles R. .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2006, 114 :106-114
[4]   Estrogenicity of butylparaben in rainbow trout Oncorhynchus mykiss exposed via food and water [J].
Alslev, B ;
Korspaard, B ;
Bjerregaard, P .
AQUATIC TOXICOLOGY, 2005, 72 (04) :295-304
[5]  
[Anonymous], 1984, J AM COLL TOXICOL, V3, P147
[6]  
[Anonymous], 2010, Opinion on Triclosan - Antimicrobial Resistance, P1, DOI DOI 10.2772/11162
[7]   Widespread occurrence of bisphenol A diglycidyl ethers, p-hydroxybenzoic acid esters (parabens), benzophenone type-UV filters, triclosan, and triclocarban in human urine from Athens, Greece [J].
Asimakopoulos, Alexandros G. ;
Thomaidis, Nikolaos S. ;
Kannan, Kurunthachalam .
SCIENCE OF THE TOTAL ENVIRONMENT, 2014, 470 :1243-1249
[8]   Systemic exposure to parabens: Pharmacokinetics, tissue distribution, excretion balance and plasma metabolites of [14C]-methyl-, propyl- and butylparaben in rats after oral, topical or subcutaneous administration [J].
Aubert, Nicolas ;
Ameller, Thibault ;
Legrand, Jean-Jacques .
FOOD AND CHEMICAL TOXICOLOGY, 2012, 50 (3-4) :445-454
[9]   Chemical toxins: A hypothesis to explain the global obesity epidemic [J].
Baillie-Hamilton, PF .
JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 2002, 8 (02) :185-192
[10]   Root specific elicitation and exudation of fluorescent β-carbolines in transformed root cultures of Oxalis tuberosa [J].
Bais, HP ;
Vepachedu, R ;
Vivanco, JM .
PLANT PHYSIOLOGY AND BIOCHEMISTRY, 2003, 41 (04) :345-353