Self-Organization of Honeycomb-like Porous TiO2 Films by means of the Breath-Figure Method for Surface Modification of Titanium Implants

被引：27

作者：

Li, Hong ^{[1
]}

Jia, Yi ^{[1
]}

Du, Mingchun ^{[2
]}

Fei, Jinbo ^{[1
]}

Zhao, Jie ^{[1
]}

Cui, Yue ^{[1
]}

Li, Junbai ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid & Interface Sci, BNLMS, Beijing 100190, Peoples R China

[2] Chinese Acad Sci, Suzhou Inst Nanotech & Nanobion, Div Nanobiomed Res, Suzhou 215123, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 17期

关键词：

breath-figure method; porosity; surface modification; thin films; titanium dioxide; PHOTONIC CRYSTALS; BLOCK-COPOLYMERS; STRUCTURED FILMS; CELL MORPHOLOGY; FOCAL ADHESION; POLYMER-FILMS; NANOPARTICLES; GROWTH; NANOTOPOGRAPHY; PHASE;

D O I：

10.1002/chem.201203353

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This study describes a facile breath-figure method for the preparation of honeycomb-like porous TiO2 films with an organometallic small-molecule precursor. Multiple characterization techniques have been used to investigate the porous films and a mechanism for the formation process of porous TiO2 films through the breath-figure method is proposed. The pore size of the TiO2 films could be modulated by varying the experimental parameters, such as the concentration of titanium n-butoxide (TBT) solution, the content of cosolvent, and the air flow rate. In vitro cell-culture experiments indicate that NIH 3T3 fibroblast cells seeded on the honeycomb-like porous TiO2 films show good adhesion, spreading, and proliferation behaviors, which suggests that honeycomb-like porous TiO2 films are an attractive biomaterial for surface modification of titanium and its alloys implants in tissue engineering to enhance their biocompatibility and bioactivity.

引用

页码：5306 / 5313

页数：8

共 49 条

[1]

Akin FA, 2001, J BIOMED MATER RES, V57, P588, DOI 10.1002/1097-4636(20011215)57:4<588::AID-JBM1206>3.0.CO

[2]

2-Y

[3] Honeycomb-structured porous films from polypyrrole-containing block copolymers prepared via RAFT polymerization as a scaffold for cell growth [J].