Parameters of Pro- and Antioxidant Status in Ejaculate of Men of Fertile Age

被引：5
|
作者：
Kolesnikova, L. I. [1 ]
Kurashova, N. A. [1 ]
Osadchuk, L. V. [2 ]
Osadchuk, A. V. [2 ]
Dolgikh, M. I. [1 ]
Dashiev, B. G. [3 ]
机构：
[1] Res Ctr Hlth Problems Family & Human Reprod, Irkutsk, Russia
[2] Russian Acad Sci, Inst Cytol & Genet, Siberian Div, Novosibirsk 630090, Russia
[3] Minist Healthcare Russian Federat, Republican Perinatal Ctr, Ulan Ude, Republic Of Bur, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2015年 / 159卷 / 06期
关键词：
lipid peroxidation; antioxidants; men; spermatogenesis; seminal fluid; SEMEN QUALITY;
D O I：
10.1007/s10517-015-3059-6
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Parameters of LPO reflecting primary and end stages of oxidation and total antioxidant activity were evaluated in the seminal fluid of young fertile men living in Novosibirsk. By the results of andrological examination and spermogram analysis, various reproductive disorders and abnormal spermogram (pathospermia) were found in 48 patients. Shifts towards activation of prooxidant processes in LPO-antioxidant defense metabolic system were observed in men with reproductive disorders and pathospermia. The results of individual estimation of coefficient of oxidative stress, an integral parameter reflecting the balance in the LPO-antioxidant defense system, attest to the development of oxidative stress in men with reproductive disorders and pathospermia.
引用
收藏
页码：726 / 728
页数：3
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