Antioxidant properties and phenolic variation in wild populations of Marrubium vulgare L. (Lamiaceae)

被引：40

作者：

Boulila, Abdennacer ^{[1
]}

Sanaa, Adnen ^{[2
]}

Ben Salem, Issam ^{[3
]}

Rokbeni, Nesrine ^{[1
]}

M'rabet, Yassine ^{[1
]}

Hosni, Karim ^{[1
]}

Fernandez, Xavier ^{[4
]}

机构：

[1] Natl Inst Res & Physicochem Anal, Lab Nat Subst LR10INRAP02, Biotechpole Sidi Thabet, Ariana 2020, Tunisia

[2] Natl Inst Appl Sci & Technol INSAT, Dept Biol, Plant Biotechnol Lab, North Urban Ctr, Tunis 1080, Tunisia

[3] Natl Ctr Nucl Sci & Technol CNSTN, Applicat Nucl Techn Fields Hlth Agr & Environm, Res Unit, Ariana 2020, Tunisia

[4] Univ Nice Sophia Antipolis, CNRS, UMR 7272, Inst Chim Nice, F-06108 Nice 2, France

来源：

INDUSTRIAL CROPS AND PRODUCTS | 2015年 / 76卷

关键词：

Marrubium vulgare; Phenolic variation; Bioclimate; Tunisia; LABDANE DITERPENES; IDENTIFICATION; CYLLENEUM; VELUTINUM; THESSALUM; LEAVES; PLANTS; HERBS; NOE;

D O I：

10.1016/j.indcrop.2015.07.069

中图分类号：

S2 [农业工程];

学科分类号：

0828 ;

摘要：

The phenolic profile of six wild growing Marrubium vulgare L. (Lamiaceae) collected from different bioclimatic zones was investigated. Ethanol, ethyl acetate and residual water fractions were investigated for their antioxidant activity using DPPH assay. Ethyle acetate (EtOAc) fraction showed the highest antioxidant capacity with IC50 values ranging from 68.98 to 118.15 mu g/mL. Eight phenolic acids and five flavonoids were detected in the ethyle acetate fraction and quantified by high performance liquid chromatography (HPLC) coupled to a diode array detector (DAD), among them the concentration of quercetin-3-D-O-galactoside (5.84-14.46 mg/g DW) was the highest. Metabolic profile, consisting of glycosylated flavonoids and phenolic acids, was very regular with only quantitative differences and absences limited to minor components. A remarkably significant quantitative variation for the major components was noted. On the basis of chemical composition, principal component analysis and cluster analysis, M. vulgare was classified into two groups. Population grouping was not concordant with bioclimatic appurtenance. These results indicate that M. vulgare can be used in dietary applications with a potential to reduce oxidative stress. The pronounced chemical diversity between populations is discussed to possibly be linked to the variation of soil properties and microclimate conditions. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：616 / 622

页数：7

共 40 条

[11] FLAVONE C-GLYCOSIDES OF PHORADENDRON-TOMENTOSUM FROM DIFFERENT HOST TREES [J].

DOSSAJI, SF ;

BECKER, H ;

EXNER, J .

PHYTOCHEMISTRY, 1983, 22 (01) :311-312

[12]

Halliwell B., 2003, FREE RADICALS BIOL M

[13]

HATANO T, 1988, CHEM PHARM BULL, V36, P2090

[14] Secondary metabolites from Marrubium velutinum, growing wild in Greece [J].

Karioti, A ;

Heilmann, J ;

Skaltsa, H .

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2005, 60 (03) :328-332

[15] Cytotoxicity and immunomodulating characteristics of labdane diterpenes from Marrubium cylleneum and Marrubium velutinum [J].

Karioti, Anastasia ;

Skopeliti, Margarita ;

Tsitsilonis, Ourania ;

Heilmann, Joerg ;

Skaltsa, Helen .

PHYTOCHEMISTRY, 2007, 68 (11) :1587-1594

[16] Identification of tyrosinase inhibitors from Marrubium velutinum and Marrubium cylleneum [J].

Karioti, Anastasia ;

Protopappa, Anastasia ;

Megoulas, Nikolaos ;

Skaltsa, Helen .

BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 15 (07) :2708-2714

[17]

KOWALEWSKI Z, 1978, HERBA POL, V24, P183

[18]

LAONIGRO G, 1979, GAZZ CHIM ITAL, V109, P145

[19]

LEWIS HL, 1977, MED BOT

[20]

Mabberley D.J., 1997, The plant book: a portable dictionary of the vascular plants

← 1 2 3 4 →