Original and rapid access to new alkaloid analogues of neocryptolepine:: Synthesis of substituted 6-methyl-6H-indolo[2,3-b]quinolines via TDAE strategy

被引:29
作者
Amiri-Attou, O [1 ]
Terme, T [1 ]
Vanelle, P [1 ]
机构
[1] Univ Mediterranee, CNRS, UMR 6517, LCOP, F-13385 Marseille 05, France
关键词
TDAE; indolo[2,3-b]quinoline; alkaloids; reduction; 1-methyl isatin;
D O I
10.1055/s-2005-921916
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
We report herein an original and rapid synthesis of new substituted 6H-indolo[2,3-b]quinolines based on TDAE strategy from reaction between substituted o-nitrobenzyl chlorides and 1-methyl isatin followed by a one-pot reduction-cyclization-dehydration reaction.
引用
收藏
页码:3047 / 3050
页数:4
相关论文
共 32 条
  • [31] Terme T., 2002, ELECT TRANSFER REACT, P1
  • [32] Timari G, 1997, SYNLETT, P1067