Probiotics: Versatile Bioactive Components in Promoting Human Health

被引:113
作者
Sharifi-Rad, Javad [1 ]
Rodrigues, Celia F. [2 ]
Stojanovic-Radic, Zorica [3 ]
Dimitrijevic, Marina [3 ]
Aleksic, Ana [3 ]
Neffe-Skocinska, Katarzyna [4 ]
Zielinska, Dorota [4 ]
Kolozyn-Krajewska, Danuta [4 ]
Salehi, Bahare [5 ,6 ]
Prabu, Selvaraj Milton [7 ]
Schutz, Francine [8 ]
Docea, Anca Oana [9 ]
Martins, Natalia [8 ,10 ,11 ]
Calina, Daniela [12 ]
机构
[1] Shahid Beheshti Univ Med Sci, Phytochem Res Ctr, Tehran 1991953381, Iran
[2] Univ Porto, Fac Engn, LEPABE Dept Chem Engn, P-4200465 Porto, Portugal
[3] Univ Nis, Fac Sci & Math, Dept Biol & Ecol, Nish 18000, Serbia
[4] Warsaw Univ Life Sci WULS, Dept Food Gastron & Food Hyg, PL-02776 Warsaw, Poland
[5] Bam Univ Med Sci, Noncommunicable Dis Res Ctr, Bam 44340847, Iran
[6] Bam Univ Med Sci, Sch Med, Student Res Comm, Bam 44340847, Iran
[7] Annamalai Univ, Dept Zool, Annamalainagar 608002, Chidambaram, India
[8] Univ Porto, Fac Med, Dept Biomed, P-4200319 Porto, Portugal
[9] Univ Med & Pharm Craiova, Dept Toxicol, Craiova 200349, Romania
[10] Univ Porto, Inst Res & Innovat Hlth i3S, P-4200135 Porto, Portugal
[11] Univ Porto, Fac Psychol & Educ Sci, Lab Neuropsychophysiol, P-4200135 Porto, Portugal
[12] Univ Med & Pharm Craiova, Dept Clin Pharm, Craiova 200349, Romania
来源
MEDICINA-LITHUANIA | 2020年 / 56卷 / 09期
基金
欧盟地平线“2020”;
关键词
nutrition; lifestyle; probiotic properties; evidence based-medicine; mechanisms; clinical studies; safety; LACTIC-ACID BACTERIA; LACTOBACILLUS-RHAMNOSUS GG; GUT MICROBIOTA; SENSORY CHARACTERISTICS; INTESTINAL MICROBIOTA; ANTIBIOTIC-RESISTANCE; FERMENTED SAUSAGES; QUALITY-ASSURANCE; POTENTIAL USES; FOOD;
D O I
10.3390/medicina56090433
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The positive impact of probiotic strains on human health has become more evident than ever before. Often delivered through food, dietary products, supplements, and drugs, different legislations for safety and efficacy issues have been prepared. Furthermore, regulatory agencies have addressed various approaches toward these products, whether they authorize claims mentioning a disease's diagnosis, prevention, or treatment. Due to the diversity of bacteria and yeast strains, strict approaches have been designed to assess for side effects and post-market surveillance. One of the most essential delivery systems of probiotics is within food, due to the great beneficial health effects of this system compared to pharmaceutical products and also due to the increasing importance of food and nutrition. Modern lifestyle or various diseases lead to an imbalance of the intestinal flora. Nonetheless, as the amount of probiotic use needs accurate calculations, different factors should also be taken into consideration. One of the novelties of this review is the presentation of the beneficial effects of the administration of probiotics as a potential adjuvant therapy in COVID-19. Thus, this paper provides an integrative overview of different aspects of probiotics, from human health care applications to safety, quality, and control.
引用
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页码:1 / 30
页数:30
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