Determinants of SR protein specificity

被引：182
作者：
Tacke, R [1 ]
Manley, JL [1 ]
机构：
[1] Columbia Univ, Dept Biol Sci, New York, NY 10027 USA
来源：
CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 03期
关键词：
D O I：
10.1016/S0955-0674(99)80050-7
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The SR (Ser-Arg) proteins are a family of nuclear factors that play multiple important roles in splicing of mRNA precursors in metazoan organisms. functioning in both constitutive and regulated splicing. Certain of these functions are redundant, such that any single SR proteins will suffice, but other functions are unique and are specific to a given family member. A number of studies during the past year have investigated the. basis for SR protein specificity.
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页码：358 / 362
页数：5
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