Numerical study of a disordered model for DNA denaturation transition

被引:16
作者
Coluzzi, B [1 ]
机构
[1] CEA Saclay, Serv Phys Theor, F-91191 Gif Sur Yvette, France
来源
PHYSICAL REVIEW E | 2006年 / 73卷 / 01期
关键词
D O I
10.1103/PhysRevE.73.011911
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
We numerically study a disordered version of the model for DNA denaturation transition consisting of two interacting self-avoiding walks in three dimensions, which undergoes a first order transition in the homogeneous case. The two possible values (epsilon) over cap (AT) and (epsilon) over cap (GC) of the interactions between base pairs are taken as quenched random variables distributed with equal probability along the chain. We measure quantities averaged over disorder such as the energy density, the specific heat, and the probability distribution of the loop lengths. When applying the scaling laws used in the homogeneous case we find that the transition seems to be smoother in the presence of disorder, in agreement with general theoretical arguments, although we cannot rule out the possibility of a first order transition.
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页数:9
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  • [1] AIZENMAN M, 1990, PHYS REV LETT, V64, P1311, DOI 10.1103/PhysRevLett.64.1311
  • [2] ROUNDING OF 1ST-ORDER PHASE-TRANSITIONS IN SYSTEMS WITH QUENCHED DISORDER
    AIZENMAN, M
    WEHR, J
    [J]. PHYSICAL REVIEW LETTERS, 1989, 62 (21) : 2503 - 2506
  • [3] Bubble nucleation and cooperativity in DNA melting
    Ares, S
    Voulgarakis, NK
    Rasmussen, KO
    Bishop, AR
    [J]. PHYSICAL REVIEW LETTERS, 2005, 94 (03)
  • [4] Interstrand distance distribution of DNA near melting
    Baiesi, M
    Carlon, E
    Kafri, Y
    Mukamel, D
    Orlandini, E
    Stella, AL
    [J]. PHYSICAL REVIEW E, 2003, 67 (02):
  • [5] Scaling in DNA unzipping models: Denaturated loops and end segments as branches of a block copolymer network
    Baiesi, M
    Carlon, E
    Stella, AL
    [J]. PHYSICAL REVIEW E, 2002, 66 (02):
  • [6] A simple model of DNA denaturation and mutually avoiding walks statistics
    Baiesi, M
    Carlon, E
    Orlandini, E
    Stella, AL
    [J]. EUROPEAN PHYSICAL JOURNAL B, 2002, 29 (01) : 129 - 134
  • [7] BELOHOREC P, UNPUB
  • [8] BERKER AN, 1993, PHYSICA A, V194, P72, DOI 10.1016/0378-4371(93)90341-Z
  • [9] Comment on "a simple model for DNA denaturation" by T. Garel, C. Monthus and H. Orland
    Bhattacharjee, SM
    [J]. EUROPHYSICS LETTERS, 2002, 57 (05): : 772 - 773
  • [10] Statistical mechanical simulation of polymeric DNA melting with MELTSIM
    Blake, RD
    Bizzaro, JW
    Blake, JD
    Day, GR
    Delcourt, SG
    Knowles, J
    Marx, KA
    SantaLucia, J
    [J]. BIOINFORMATICS, 1999, 15 (05) : 370 - 375