Synthesis and Bioactivity of Three-Ring Heterocyclic Schiff Base Derivatives

被引：2

作者：

Xiong, Zhuang ^{[1
]}

Li, Haichang ^{[1
]}

Liang, Na ^{[1
]}

Yin, Juan ^{[1
]}

Lu, Ping ^{[1
]}

Xue, Wei ^{[1
]}

机构：

[1] Guizhou Univ, Key Lab Green Pesticide & Bioengn, Minist Educ, Res & Dev Ctr Fine Chem, Guiyang 550025, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 32卷 / 08期

基金：

中国国家自然科学基金;

关键词：

triazole; pyridazinone; bioactivity; synthesis; BIOLOGICAL-ACTIVITIES;

D O I：

10.6023/cjoc1112241

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ten novel three-ring heterocyclic Schiff-base derivatives were designed and synthesized. Their structures of all these compounds were confirmed by H-1 NMR, C-13 NMR, IR spectra and elemental analysis. The preliminary result of bioassay showed that the title compounds exhibited some degree of antifungal activities on G zeae, C. mandshurica and F. oxysporum under 50 mg/L concentration.

引用

页码：1473 / 1478

页数：6

共 15 条

[1] Bagrak H., 2009, EUR J MED CHEM, V44, P1057
[2] Bai K, 2010, CHINESE J ORG CHEM, V30, P1255
[3] Cao LH, 2006, CHINESE J ORG CHEM, V26, P1686
[4] Chai B., 2009, AGROCHEMICALS, V48, P13
[5] Synthesis of some novel 2-substituted-5-[isopropylthiazole] clubbed 1,2,4-triazole and 1,3,4-oxadiazoles as potential antimicrobial and antitubercular agents
Kumar, G. V. Suresh
Rajendraprasad, Y.
Mallikarjuna, B. P.
Chandrashekar, S. M.
Kistayya, C.
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (05) : 2063 - 2074
[6] Li QZ, 2010, CHINESE J ORG CHEM, V30, P569
[7] Li YJ, 2010, ACTA CHIM SINICA, V68, P1577
[8] MKarthikeyan M. S., 2006, BIOORGAN MED CHEM, V14, P7482
[9] Sun XH, 2008, ACTA CHIM SINICA, V66, P234
[10] Sun XH, 2011, CHEM J CHINESE U, V32, P1312

← 1 2 →