A facile synthesis of novel triazabicyclic molecules as potential bicyclic templates for pharmaceutical ligands by the ring opening metathesis-cross metathesis of triazatricyclo[3.2.1.02,6]dec-8-ene-3,5-diones

被引:0
|
作者
Anas, Saithalavi [1 ]
Sarika, Chechattil [1 ]
Rajan, Rani [1 ]
Radhakrishnan, K. V. [1 ]
机构
[1] Natl Inst Interdisciplinary Sci & Technol, CSIR, Chem Sci & Technol Div, Organ Chem Sect, Trivandrum 695019, Kerala, India
来源
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2008年 / 47卷 / 07期
关键词
ring opening metathesis-cross metathesis; Grubb's catalyst; 1,2,4-triazoline-3,5-diones; triazabicyclic molecules;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Novel multifunctional triazabicyclic molecules are synthesized in excellent yields by the ring opening metathesis-cross metathesis of triazatricyclo [3.2.1.0(2,6)]dec-8-ene-3,5-diones with various terminal olefins. The rigid synthesized molecules can be used as potential bicyclic templates for a number of pharmaceutically important ligands.
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页码:1063 / 1070
页数:8
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